KIDNEY TRANSPLANTATION

This study tests whether personalized education and regular phone counseling can help kidney transplant recipients take their anti-rejection medication as prescribed. Sixty adult kidney transplant patients will be split into two groups: one receives the extra support, the other g…

This study looks at a drug called imlifidase that temporarily removes harmful antibodies from the blood, allowing highly sensitized kidney patients to receive a transplant from a donor they would otherwise reject. About 450 adults who are unlikely to get a kidney through standard…

This study will check if a muscle ultrasound can reliably detect muscle loss (sarcopenia) in 140 adults getting a kidney transplant. Researchers will compare ultrasound results with a standard body-composition test before and up to one year after transplant. If it works, this cou…

This study tests whether a lower dose of the antibiotic TMP-SMX works as well as the standard dose to prevent a serious lung infection called PJP in people who have just had a kidney transplant. About 1,084 adult first-time kidney transplant recipients will take either a low or s…

This study compares a new 'tubeless' anesthesia method (using a laryngeal mask and lighter sedation) to standard breathing-tube anesthesia in 60 kidney transplant patients. The goal is to see if it reduces the need for muscle relaxants and other drugs, and improves recovery. Part…

This study follows 150 adults waiting for a kidney transplant to track how their physical and emotional health changes over time. Researchers will use a mobile app and interviews to measure frailty and quality of life. The goal is to identify patients who need extra support and i…

This study aims to develop and test advanced MRI methods to study kidney disease, including in patients with chronic kidney disease, those on dialysis, and kidney transplant recipients. Researchers will also use brain MRI to explore links between kidney function and cognitive pro…

APT-KIDNEY is a large, flexible clinical trial platform designed to test multiple treatments for advanced kidney disease more efficiently. It will enroll up to 5,000 adults with severe kidney problems or those on dialysis. By using electronic health records and adaptive methods, …

This study interviews 15 people who have donated a kidney to understand their feelings about receiving a symbolic token of gratitude, like a commemorative medal. Researchers want to know if such recognition could improve donors' experience and encourage more donations. The study …

This study looks at how cytomegalovirus (CMV) infection changes the immune system's ability to fight other infections in kidney transplant patients. Researchers will take blood samples from 60 participants, both before and after CMV infection, to measure immune cell responses. Th…

This study aims to understand how BK virus spreads in people who have received a kidney transplant. Researchers will collect saliva, urine, and blood samples from 100 adult kidney transplant recipients at several time points over one year. By measuring the virus in these samples,…