KIDNEY STONE

This study compares two common surgical techniques for removing kidney stones: one using a vacuum-assisted sheath and the other using a standard sheath. About 90 adults with kidney stones between 10-25 mm will take part. The goal is to see which method clears more stones and caus…

This trial tests a new device called VISOR for removing kidney stones in 20 adults aged 18-80 with stones 1-3 cm. The tool breaks stones and suctions out fragments while keeping kidney pressure safe. The main goal is to see if at least 9 out of 10 people are stone-free within 24 …

This study tests whether giving a diuretic (furosemide) and extra fluids during laser kidney stone surgery helps flush out smaller stone fragments. About 374 adults needing this surgery will be randomly assigned to receive either the diuretic or standard care. The main goal is to…

This study is testing a special suction tube attached to a flexible camera to remove kidney stones from the lower part of the kidney. About 33 adults with lower calyx stones will get this procedure. The main goal is to see if the new tool clears more stones than standard methods.

This study compares two long-acting diuretics (indapamide and chlorthalidone) against a standard short-acting one (hydrochlorothiazide) to see which better prevents calcium kidney stones. About 99 adults with a history of recurrent stones will take each drug in a random order. Th…

This study tests whether a DASH-style diet (rich in fruits, vegetables, and low-fat dairy) can reduce the risk of forming new kidney stones. About 48 adults with a history of kidney stones will eat either a DASH diet or a typical Western diet for one week, with all meals provided…

This study compares two doses of tadalafil (2.5 mg vs 5 mg) combined with tamsulosin to reduce symptoms caused by ureteric stents placed after kidney stone removal. About 140 adults will take one of the two combinations for several weeks. The goal is to see if the lower dose work…

This study tests a new type of ureteric stent designed to cause less pain, infection, and blockage than standard stents. About 50 adults who need a stent for kidney stones or cancer will receive the new stent and be monitored for complications. The goal is to see if the new stent…

This pilot study tests whether giving the anti-inflammatory drug Ketorolac before surgery can reduce pain and discomfort from ureteral stents placed after kidney stone treatment. About 36 adults will be randomly assigned to receive the drug or a placebo. The goal is to see if thi…

This study compares two FDA-approved lasers (Holmium:YAG with MOSES and thulium fiber) for breaking large kidney stones during a minimally invasive surgery called mini-PCNL. About 150 adults with stones larger than 15mm will be randomly assigned to one laser, both using a suction…

This study looks at whether leaving out a ureteral stent after kidney stone surgery leads to less pain and fewer doctor visits compared to placing one. About 184 adults with kidney or ureteral stones will be randomly assigned to either get a stent or not after their procedure. Th…

This study looks at how two natural compounds in food—oxalate and citrate—interact in the body and affect kidney stone risk. Researchers will measure changes in urine levels after giving potassium citrate to 24 adults, some with a history of kidney stones and some without. The go…

This study looks at how two natural compounds in food—oxalate and citrate—affect the chance of forming kidney stones. Researchers will measure changes in urine after participants consume sodium oxalate. The goal is to better understand why some people get stones and others don't.…

This observational study looks at how kidney stones, insulin resistance, and inflammation are related. Researchers will measure belly fat and blood markers in 20 people who have had calcium kidney stones (but not diabetes) and 20 healthy people. The goal is to understand why kidn…

This study looks at whether giving surgeons live information about pressure inside the kidney helps them make better decisions during stone-removal surgery. About 80 adults with large kidney stones will take part. The main goal is to see if the pressure data changes how the surge…

This study looks at how vitamin C (ascorbic acid) breaks down into oxalate, a key component of kidney stones. Researchers will give a special labeled vitamin C to 136 adults, both with and without kidney stones, and measure how much turns into oxalate in urine. The goal is to und…