KIDNEY CANCER

This study aimed to test a new gel called PuraBond, designed to quickly stop bleeding and help tissue heal after surgeons remove part of a kidney to treat cancer. The gel would have been tested in patients undergoing robotic surgery where standard methods to stop bleeding were no…

This study tests whether using a patient's own blood during kidney cancer surgery can reduce the need for donor blood transfusions. Researchers are comparing standard blood management against techniques that recycle or dilute the patient's blood during the operation. The goal is …

This study aimed to see if adding acarbose, a common diabetes medication, to standard immunotherapy is safe and tolerable for people with advanced kidney cancer that has spread. Researchers also wanted to check if acarbose changes the gut's bacteria (microbiome) and if the combin…

This early-stage study aims to find out if combining an experimental oral drug called AZD6244 with standard chemotherapy is safe and tolerable for people with advanced solid tumors like breast, colon, lung, and kidney cancer. Researchers will test different doses to find the high…

This study is testing a device that uses focused sound waves to destroy small kidney tumors without making any cuts. It enrolled 67 adults with single, small kidney tumors to see if the treatment safely eliminates the tumor tissue. Researchers will follow participants for five ye…

This study is testing if a robotic surgery for kidney cancer can be done without using stitches to close the wound. Instead, surgeons use controlled heat (cautery) to seal the area. Researchers want to see if this 'sutureless' method is just as safe and effective as the standard …

This early-stage study is testing the safety of a new, personalized vaccine designed to stop kidney cancer from returning after surgery. The vaccine is custom-made for each patient using unique markers from their own tumor. Researchers combine this vaccine with an approved immuno…

This study is testing whether a targeted radiation drug called 177Lu-PSMA-617 can help control advanced kidney cancer that has spread. The treatment works by seeking out cancer cells and delivering radiation directly to them. The trial involves about 24 patients whose cancer has …

This study aims to find the best order to give three existing kidney cancer drugs to patients whose cancer has spread. Researchers are testing six different two-drug sequences to see which order works best to control the disease and is safest. The trial involves 180 patients with…

This study is testing the safety and performance of Medtronic's new Hugo robotic surgery system for urologic procedures, primarily for cancers of the bladder, prostate, and kidney. It will enroll 144 adult patients needing specific cancer surgeries to see if the robot can complet…

This study is testing whether combining a targeted radiation drug (177Lu-girentuximab) with an immunotherapy drug (nivolumab) is safe and effective for treating advanced kidney cancer that has a specific protein (CAIX). It is for adults with clear cell kidney cancer that has spre…

This study is testing whether a 12-week support program can be successfully added to regular follow-up care for men living with advanced cancers of the prostate, kidney, bladder, testicles, or penis. The program includes nutrition advice, physical therapy, and other support servi…

This study aims to determine if measuring two specific proteins (MMP2 and MMP9) in blood can help predict how well patients with metastatic kidney cancer will respond to anti-angiogenic drugs like Sunitinib or Pazopanib. Researchers will compare protein levels in 50 patients rece…

This early-stage study is testing a tiny, implantable device to see if it can safely help doctors figure out which cancer drugs work best for an individual's kidney tumor. The device, placed into a tumor before surgery, releases tiny amounts of 19 different drugs already used to …

This study is testing a new system designed to give doctors a more complete picture of an older patient's overall health and life circumstances when planning cancer treatment. It combines questions about aging, daily function, mental health, and social needs like housing and food…