INVASIVE BREAST CANCER
Clinical trials for INVASIVE BREAST CANCER explained in plain language.
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New hope: targeted drug olaparib shows promise for Hard-to-Treat breast cancer
Disease control OngoingThis study tests a drug called olaparib in people with metastatic breast cancer that has spread beyond the breast. Participants must have a specific genetic change in their tumor that may make it sensitive to this drug. The goal is to see if olaparib can shrink tumors or slow can…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated May 26, 2026 03:15 UTC
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Could a week of radiation be enough? new study tests shorter breast cancer treatment
Disease control OngoingThis study tests whether a 1-week course of radiation after breast-conserving surgery works as well as the standard 3-week course for early-stage breast cancer. About 72 adults with ductal carcinoma in situ or early invasive breast cancer will be enrolled. The goal is to see if t…
Matched conditions: INVASIVE BREAST CANCER
Phase: NA • Sponsor: Coordinación de Investigación en Salud, Mexico • Aim: Disease control
Last updated May 26, 2026 03:14 UTC
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New combo shows promise against tough breast cancer
Disease control OngoingThis study tests a new drug called onvansertib combined with standard chemotherapy (paclitaxel) in people with triple-negative breast cancer that has spread to other parts of the body. About 50 adults with advanced disease are participating to see if the combination is safe and c…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Antonio Giordano, MD • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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Immunotherapy before surgery shows promise for aggressive breast cancer
Disease control OngoingThis study tests whether the immunotherapy drug cemiplimab, given before surgery, can eliminate all signs of cancer in high-risk or locally advanced breast cancer patients. It includes 36 adults with hormone receptor-positive or triple-negative breast cancer that has not spread t…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 26, 2026 03:08 UTC
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Shorter radiation during breast cancer surgery shows promise for older women
Disease control OngoingThis study looks at giving a single dose of radiation directly to the tumor site during breast-conserving surgery for early-stage breast cancer. It involves women aged 60 and older with small, hormone-sensitive tumors. The goal is to see if this shorter, more precise radiation ap…
Matched conditions: INVASIVE BREAST CANCER
Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Disease control
Last updated May 26, 2026 03:03 UTC
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New combo therapy shows promise for Tough-to-Treat breast cancer
Disease control OngoingThis study tests whether adding pembrolizumab (Keytruda) to sacituzumab govitecan helps people with a certain type of advanced breast cancer (HR+/HER2-) live longer without the disease getting worse. About 110 participants will receive either the drug alone or the combination. Th…
Matched conditions: INVASIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Ana C Garrido-Castro, MD • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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Blood test may tame Chemo's nerve pain
Knowledge-focused TerminatedThis study looks at whether regularly measuring the amount of paclitaxel (a chemotherapy drug) in the blood can help doctors give the right dose to kill cancer while limiting nerve damage. About 22 adults with various solid tumors (like lung, breast, or ovarian cancer) will have …
Matched conditions: INVASIVE BREAST CANCER
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 03:12 UTC
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Lab-Grown mini tumors could guide surgeons to cancer cells
Knowledge-focused OngoingThis study takes tumor samples from 50 women with invasive breast cancer to grow 3D mini-tumors (organoids) in the lab. These organoids are used to collect tiny particles called extracellular vesicles, which naturally seek out cancer cells. The goal is to see if these particles c…
Matched conditions: INVASIVE BREAST CANCER
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Knowledge-focused
Last updated May 26, 2026 03:11 UTC