INFLAMMATORY RESPONSE

This study tested whether giving the steroid methylprednisolone to infants before and during heart surgery could reduce dangerous inflammation and improve recovery. Over 1,200 infants under one year old were randomly assigned to receive either the steroid or a placebo. Researcher…

This study looked at whether the flu vaccine can reduce inflammation in people with stable coronary artery disease. Inflammation plays a key role in heart disease progression. Researchers measured blood markers of inflammation in 47 older adults before and after vaccination. The …

This study tested whether giving a single high dose of a steroid (glucocorticoid) to people having a major heart attack, before they receive standard artery-opening treatment, can reduce the amount of permanent heart muscle damage. The trial involved 530 adults with a specific ty…

This study looked at whether a sedative called dexmedetomidine can protect the brain during surgery to remove a brain tumor. 56 adults having brain tumor surgery received either the drug or a placebo. The goal was to see if the drug reduces brain injury and helps with recovery.

This study tested whether a gentle massage technique called manual lymphatic drainage is safe and practical for patients recovering from septic shock. The goal was to see if it could help improve organ function and reduce complications. The trial involved 24 adults in the intensi…

This study tested whether giving a single high dose of corticosteroids before major surgery helps elderly patients (60+) recover faster. The goal was to reduce muscle weakness and improve overall recovery. 751 participants were randomly assigned to receive either the steroid or n…

This study examined 16 ICU patients with sepsis to see if certain memory immune cells (called CD8+ T cells) are linked to how severe the infection is and the risk of dying. Researchers measured these cells in blood samples taken over 72 hours and tracked patient outcomes like len…

This study looked at how eating egg whites, egg yolks, or whole eggs every day for four weeks changes HDL (good cholesterol) and immune cell profiles in younger (18-30) and older (50-75) adults. 44 healthy men and women participated, following a healthy diet and providing blood s…

This study looked at 264 people with chronic back and leg pain caused by a pinched nerve. Researchers wanted to see if routine blood test results could predict who would get good pain relief from a combination of two treatments: pulsed radiofrequency and a steroid injection. The …

This study followed 72 newborns who had seizures shortly after birth to see if inflammation plays a role in later developing epilepsy. Researchers measured seizure activity and checked how many children later developed epilepsy. The goal was to better understand the link between …

This study tested whether a PENG block (a type of nerve block) can reduce inflammation and improve survival in 60 older adults (over 65) having hip fracture surgery. Researchers measured blood markers of inflammation and tracked deaths within 30 days. The goal was to see if this …