Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Steroid shot before surgery may speed up recovery in seniors

NCT ID NCT05220319

Symptom relief Sponsor: Ziekenhuis Oost-Limburg Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving a single high dose of corticosteroids before major surgery helps elderly patients (60+) recover faster. The goal was to reduce muscle weakness and improve overall recovery. 751 participants were randomly assigned to receive either the steroid or no steroid before their operation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

751 people

The number who actually took part.

Started

Feb 2022

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 60 years or older. * Scheduled for one of the predefined surgical procedures: * off-pump coronary bypass surgery * on-pump coronary bypass surgery * aortic and mitral valve replacement * laparoscopic hemicolectomies * thoracoscopic lung resections * femoral popliteal and tibial bypass surgery and femoral profundoplasty * laparoscopic radical prostatectomies Exclusion Criteria: * Lack of informed consent or inability to give informed consent. * Severe postoperative nausea \& vomiting (PONV), needing corticosteroids as PONV prophylaxis. * Urgent, not elective surgery * Hypersensitivity or known allergic reactions to methylprednisolone * Preoperative systemic use of steroids: * Including, but not limited to, the use of corticosteroids \> 4 weeks before surgery of at least 4 mg methylprednisolone equivalents. * Excluding inhalational and topical steroids * Preexisting muscle disease o Including, but not limited to: Steinert's disease, amyotrophic lateral sclerosis (ALS), Duchenne dystrophy, amputation of dominant arm or hand.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Inflammatory response are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

inflammatory disease Muscle Weakness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inflammatory response Weakness, muscle

Contacts and locations

Locations

  • Ziekenhuis Oost-Limburg

    Genk, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.