Egg study reveals Age-Based differences in HDL and immune response
NCT ID NCT06086795
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how eating egg whites, egg yolks, or whole eggs every day for four weeks changes HDL (good cholesterol) and immune cell profiles in younger (18-30) and older (50-75) adults. Participants followed a healthy diet and gave blood samples. The goal was to see if different egg parts affect these markers differently by age.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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44 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-30 years old, or 50-75 years old (at time of screening) * Body mass index (BMI) \< 30 kg/m2 * Willing to consume whole eggs, egg whites, or egg yolks on a daily basis during study periods, and refrain from eating eggs during other study periods * Do not fit any exclusion criteria Exclusion Criteria: * \< 18 years old; 31-49 years old; \> 75 years old * BMI ≥ 30 kg/m2 or body weight \< 110 pounds * Weight changes \> 10% over the last 4 weeks * Self-reported history of diabetes, heart disease, stroke, renal or liver disease, cancer, eating disorders, certain severe and/or relapsing/remitting autoimmune, inflammatory, or metabolic diseases, chronic infections, scleroderma, blood clotting disorders, intravenous drug use, or current pregnancy or lactation * Allergy or intolerance to eggs, egg components, or egg products * Implanted medical device (e.g., pacemaker) or other health condition that would prevent measurement of body composition by bioelectrical impedance * Highly elevated fasting lipid and glucose levels (triglyceride levels higher than 500 mg/dL, fasting glucose higher than 126 mg/dL), or total cholesterol \< 120 mg/dL and HDL-cholesterol \< 15 mg/dL * Currently taking lipid-lowering medications (e.g. statins, fibrates), anti-inflammatory medications (e.g., NSAIDs, corticosteroids), or medications that primarily affect blood clotting (e.g., warfarin)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Connecticut
Storrs, Connecticut, 06269, United States
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Other studies related to the condition(s) this trial covers.
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