HYPOGLYCEMIA

This early-phase study tests a new treatment called OPF-310, which uses pig islet cells (the cells that make insulin) placed inside tiny capsules. The goal is to see if transplanting these cells is safe and can help adults with unstable type 1 diabetes who still have dangerous lo…

This study aims to better understand and treat fasting hypoglycemia, a condition where blood sugar drops too low. Researchers will test 1,500 adults with documented low blood sugar or insulin-secreting tumors. Participants undergo supervised fasting and blood tests to find the ca…

This study tests if a special stent placed through an endoscope can reverse a gastric bypass in people who have serious complications like low blood sugar, blockages, or liver problems. The goal is to see if this less invasive approach works as well as surgery. About 20 adults wh…

This study tests whether a wearable breath sensor can detect high or low blood sugar (hyperglycemia or hypoglycemia) in teens with type 1 diabetes. Participants wear the device for 72 hours and provide breath samples while their blood sugar is measured. The goal is to find a noni…

This small pilot study is testing a new in-ear wearable device that measures blood flow to the head. Researchers want to see if it can help detect low blood sugar episodes in people who have had bariatric surgery. The study involves 5 participants and focuses on whether the devic…

This early-phase study looks at how a natural protein called C-peptide might help people with type 1 diabetes recover faster from low blood sugar (hypoglycemia). Researchers will measure hormone levels and liver sugar production in 38 adults. The goal is to understand if C-peptid…

This study looks at whether a special computer program can help doctors better manage blood sugar levels in hospitalized adults. The tool alerts care teams when a patient's blood sugar is too high or too low, so they can act quickly. Researchers will track how long patients stay …

This study looks at why some people who had gastric bypass surgery develop very low blood sugar years later, while others see their type 2 diabetes improve. Researchers will measure gut hormones and nerve signals to understand how the surgery changes insulin release. The study in…

This study looks at how different levels of low blood sugar (hypoglycemia) affect blood vessels and inflammation in healthy people. Researchers will measure changes in artery function before and after controlled low blood sugar. The goal is to understand the body's response, not …

This study looks at whether sexual activity increases the risk of low blood sugar (hypoglycemia) in adults with type 1 or type 2 diabetes who use insulin and a continuous glucose monitor (CGM). One hundred participants will mark sexual activity in their CGM app for 3 months. Rese…

This study tests a digital tool called CGM ASSIST that helps people with Alzheimer's or dementia and diabetes, along with their caregivers and doctors, better understand blood sugar levels. Participants wear a continuous glucose monitor for 14 days and use easy-to-read displays t…

This study looks at whether the standard A1C blood sugar test is accurate for people with type 2 diabetes who have a Left Ventricular Assist Device (LVAD). Researchers will compare A1C results with data from a continuous glucose monitor (CGM) worn for 3 months. The goal is to see…