HUNTINGTON DISEASE
Clinical trials for HUNTINGTON DISEASE explained in plain language.
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Huntington's drug votoplam tested for Long-Term safety
Disease control OngoingThis study looks at the long-term safety and effects of the drug votoplam in people with Huntington's disease. About 144 participants who completed a previous votoplam study will receive the drug for up to 48 months. Researchers will monitor side effects and measure changes in br…
Matched conditions: HUNTINGTON DISEASE
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 02:51 UTC
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Gene therapy trial targets Huntington's disease in 5 patients
Disease control OngoingThis early-stage trial tests a gene therapy called AB-1001 in 5 adults with early Huntington's disease. The therapy is injected directly into the brain to try to slow the disease. The main goal is to check safety and side effects, while also looking at brain changes on MRI scans.
Matched conditions: HUNTINGTON DISEASE
Phase: PHASE1, PHASE2 • Sponsor: AskBio France, SAS, a subsidiary of AskBio Inc. • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Hope for Huntington's: new drug trial targets early stages
Disease control OngoingThis study tests a drug called tominersen in people with early Huntington's disease. The goal is to see if it can slow the disease by lowering a harmful protein in the brain. About 300 participants will receive either the drug or a placebo, and researchers will monitor safety and…
Matched conditions: HUNTINGTON DISEASE
Phase: PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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New Huntington's drug enters early human testing
Disease control OngoingThis early-phase study tests an experimental drug called ER2001 in 27 adults with early-stage Huntington's disease. The main goal is to check safety and how the drug moves through the body. Participants receive either the drug or a placebo as an IV once a week for 6 weeks, with f…
Matched conditions: HUNTINGTON DISEASE
Phase: PHASE1, PHASE2 • Sponsor: ExoRNA Bioscience • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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New pill aims to tackle Huntington's at its source
Disease control OngoingThis study tests an oral drug called SKY-0515 in 120 adults with Huntington's disease. The goal is to see if it can lower a harmful protein linked to the disease and improve symptoms. Participants take the drug or a placebo for a set period, and researchers monitor changes in pro…
Matched conditions: HUNTINGTON DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Skyhawk Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 12:00 UTC
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Huntington's drug shows promise for speech and movement
Symptom relief OngoingThis study tests whether deutetrabenazine can help improve speech clarity and walking ability in people with Huntington disease. Researchers will measure how well participants can speak and move before and after taking the drug. The goal is to see if this medication can ease thes…
Matched conditions: HUNTINGTON DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 18, 2026 11:58 UTC
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New brain scans reveal hidden changes years before Huntington's symptoms appear
Knowledge-focused OngoingThis study looks at 40 people with early-stage Huntington's disease and healthy volunteers to see how well two types of brain scans can detect changes over 2 years. Participants get PET and MRI scans plus clinical exams at the start and after 2 years. The goal is to find better w…
Matched conditions: HUNTINGTON DISEASE
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated May 26, 2026 02:45 UTC