HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Clinical trials for HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA explained in plain language.
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New pill shows promise for Hard-to-Treat breast cancer in early trial
Disease control Recruiting nowThis early-phase study tests a new drug called BGB-43395, which blocks a protein (CDK4) that helps cancer cells grow. It is for people with advanced hormone receptor-positive, HER2-negative breast cancer or other solid tumors that have spread. The study aims to find the safest an…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated May 26, 2026 08:00 UTC
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Immunotherapy boost may stop High-Risk breast cancer return
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (durvalumab) to standard chemotherapy can prevent breast cancer from coming back in people with a high-risk form of hormone receptor-positive, HER2-negative breast cancer. About 3,680 adults with stage II or III breast cancer …
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New hope for hard-to-treat breast cancer: targeted drug takes on standard therapy
Disease control Recruiting nowThis study tests a targeted drug, trastuzumab deruxtecan (T-DXd), against the usual treatment (a CDK4/6 inhibitor plus hormone therapy) for people with a specific type of advanced breast cancer. The cancer must be hormone receptor-positive, HER2-low or ultralow, and have a non-lu…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: MedSIR • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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New drug combo aims to wipe out HER2 low breast cancer before surgery
Disease control Recruiting nowThis study tests a drug called trastuzumab deruxtecan, which delivers chemotherapy directly to cancer cells with low HER2 levels, given alone or with anastrozole (a hormone blocker). About 88 people with early-stage, hormone receptor positive breast cancer will receive treatment …
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Smart bag and texts aim to boost Pill-Taking in advanced breast cancer
Symptom relief Recruiting nowThis study tests a system called CONCURxP that uses a special medication bag (WiseBag) and text message reminders to help people with metastatic breast cancer take their CDK4/6 inhibitor pills correctly. About 410 patients will either use the bag alone or the bag plus text remind…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Symptom relief
Last updated May 26, 2026 07:51 UTC
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Needles vs. pain: new study aims to keep black women on lifesaving breast cancer meds
Symptom relief Recruiting nowThis study tests whether in-person acupuncture or virtual acupressure can prevent the joint pain that often causes Black women to stop taking their breast cancer hormone therapy. About 150 Non-Hispanic Black postmenopausal women with early-stage breast cancer will be enrolled. Th…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: Emory University • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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New hope for seniors: tolerability trial for advanced breast cancer drug
Symptom relief Recruiting nowThis study looks at how well older adults (70+) with hormone receptor positive metastatic breast cancer tolerate the drug abemaciclib after other treatments have stopped working. The main goal is to track side effects and see if the drug can be safely combined with hormone therap…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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Can a vaginal moisturizer ease breast cancer side effects?
Symptom relief Recruiting nowThis study tests whether Revaree Plus, a vaginal moisturizer, can improve vaginal dryness in women with hormone-receptor-positive breast cancer. About 60 participants who have completed primary cancer therapy or are on maintenance treatment will use the product for 8 weeks. The g…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE4 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated May 12, 2026 13:39 UTC
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Breast cancer and sleepless nights: new study investigates the link
Knowledge-focused Recruiting nowThis study looks at how sleep changes in women with early-stage breast cancer during treatment. Researchers will track sleep patterns and quality in 100 participants before, during, and after chemotherapy or radiation. The goal is to understand why sleep problems happen and how s…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 07:26 UTC