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Gentle tai chi may soothe joint pain caused by breast cancer treatment

NCT ID NCT07737951

Symptom relief Sponsor: Thomas Jefferson University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This pilot trial tests whether a 12-week virtual tai chi program can reduce joint pain in postmenopausal women with hormone receptor-positive breast cancer who are taking aromatase inhibitors. Participants are randomly assigned to tai chi classes or health education sessions. The study measures feasibility, satisfaction, and changes in pain and function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tai Chi (virtual group classes via Zoom, twice weekly for 12 weeks)
What this could lead to
If it works, this could offer a drug-free way to manage joint pain for breast cancer survivors on aromatase inhibitors.
What could go wrong
This is a small pilot study focused on feasibility, not proof of effectiveness. Results may not apply to all survivors, and the virtual format may not suit everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: -Individuals must meet all the following inclusion criteria in order to be eligible to participate in the study: * Age ≥18 years * Diagnosis of stage I-III hormone receptor-positive breast cancer * Postmenopausal * Currently receiving an aromatase inhibitor (anastrozole, letrozole, or exemestane) or within 5 years of initiation * Report joint pain that started or worsened after initiation of AI therapy * Report worst pain in the past week ≥3 on the BPI (0-10 scale) * Able to complete study procedures in English * Willing to be randomized to an intervention or attention control group and adhere to study procedures Exclusion Criteria: -An individual who meets any of the following criteria will be excluded from participation in this study: * Undergoing active cancer treatment (excluding endocrine therapy) * Uncontrolled cardiac or pulmonary disease that would limit safe participation * Currently engaged in regular structured moderate- or vigorous-intensity exercise (e.g., brisk walking, jogging/running, cycling, swimming, aerobic classes, or resistance training) totaling ≥150 minutes per week over the past 3 months * Currently participating in Tai Chi, yoga, Pilates, or other structured mind-body practice ≥2 times per week over the past 3 months * Joint pain due to inflammatory arthritic conditions * Recent surgery or joint injection within the past 4-6 weeks * Initiation or dose change of corticosteroids or opioids within the past 4 weeks * Planned discontinuation of AI therapy within the next 6 months * This study is limited to women with breast cancer, as \<1% of cases occur in men and data on AIIA in male patients are limited

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Hormone receptor-positive breast carcinoma Postmenopausal

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sidney Kimmel Cancer Center at Thomas Jefferson University

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

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