HIV/AIDS

This study is testing a new mobile health system that sends text reminders and offers support to help women with HIV stick to their treatment plan. The goal is to reduce stigma and medical mistrust while improving clinic attendance and medication adherence. About 80 women will ta…

This study tests a program called Mlambe for married couples in Malawi where one partner drinks heavily and at least one has HIV. The program combines savings accounts, financial training, and relationship skills to help couples reduce alcohol use and improve HIV management. Rese…

This study tests new treatments to help people with HIV quit smoking. Smoking is a major health risk for this group, causing more harm than HIV itself. The study will compare different approaches, including medication and support, to find what works best. About 340 adults with HI…

This study tests whether daily text reminders and small financial rewards can help people with HIV take their medication consistently. Researchers will enroll 550 adults in Uganda who recently started HIV treatment. Participants will receive text messages and incentives for up to…

This study tests a system that uses a special pill sensor to track when HIV medication is taken. If doses are missed, the system alerts a care team who can help with social issues like food or housing that might be getting in the way. The goal is to see if this approach helps 110…

This study tests a program called ARC that helps HIV clinics improve their work environment and reduce racial bias. About 1,500 people with HIV from 12 Philadelphia clinics will take part. The goal is to see if these changes help more patients stay in care and achieve viral suppr…

This study tests a 4-month online program called Women SHINE for 360 women living with HIV who have experienced violence and struggle to take their HIV medication regularly. The program includes one-on-one sessions with a peer navigator, support groups, and online resources. The …

This study tests a program called ADELANTE for Latino adults with HIV whose virus is not well-controlled. Participants will either receive five sessions with a community health worker who helps solve problems, or five reminder phone calls. The goal is to see if the program helps …

This study works with over 1,200 young people (ages 14-24) in Nigeria to see how to keep HIV self-testing and prevention services running long-term. Researchers will compare standard services versus those with extra support to help community groups sustain these programs. The goa…

This study combines peer navigation (trained community members) with a mobile health app to help gay, bisexual, and transgender people in rural Appalachia access HIV, STI, and hepatitis C testing and prevention services. About 141 participants will be split into two groups: one g…

This study tests whether a mobile app called MyPEEPS can help prevent HIV infections in 3,200 young men who have sex with men and non-binary individuals (ages 16-29) who are at high risk. Participants will use the app or receive standard care, and researchers will track new HIV c…

This study looks at whether a brief alcohol counseling program can help heavy drinkers in Kenya and Uganda stay on HIV prevention medications like PrEP and PEP. About 400 adults who are at high risk for HIV and drink heavily will take part. The goal is to see if the counseling im…

This study tests whether a program led by peers (trained community members) can help women at high risk for HIV use prevention methods like PrEP more consistently. About 60 HIV-negative women in Uganda will receive the program and be followed for 6 months. The goal is to see if t…

This study tests a program called PrEP My Way, designed to help young women aged 16-24 in Kisumu, Kenya, continue using HIV prevention medicine. Participants can choose between a daily pill, a long-acting injection, or a vaginal ring, along with support from peers. The goal is to…

This study tests whether a mobile app plus virtual peer support can help young men (ages 16-25) who are at high risk for HIV start and stick with PrEP, a daily pill that prevents HIV. The study enrolls 500 HIV-negative participants across the U.S. who own a smartphone and have ha…

This study aims to find out if two types of HIV medications (NNRTI and INSTI) cause different levels of fatty liver disease in people with HIV. Researchers will screen 200 HIV patients using ultrasound to measure liver fat and stiffness. The goal is to learn which drug class may …

This study looks at what happens in the body when people with HIV temporarily stop their medication. Volunteers pause antiretroviral therapy (ART) and have frequent check-ups. Most restart treatment within three weeks, even if the virus doesn't come back. The goal is to learn mor…

This study looks at the tiny organisms (microbes) living in the lungs of people with active tuberculosis (TB). Researchers want to understand how these microbes change with treatment and affect the body's immune response. They will study 150 adults, including those with TB and he…