HEMATOLOGIC DISEASES

This study looked at adding a new drug, asciminib, to the standard treatment imatinib for people with chronic myeloid leukemia (CML) who hadn't reached very low levels of cancer cells. 104 adults who had been on imatinib for at least a year were randomly assigned to add asciminib…

This study tested a one-time treatment using CRISPR gene editing to fix a patient's own blood stem cells, aiming to help people with severe beta-thalassemia stop needing regular blood transfusions. 59 participants received the modified cells after a short course of chemotherapy. …

This early-phase study tested a new treatment called RD13-02, which uses a patient's own immune cells modified to attack cancer cells with a specific marker (CD7). It involved just 2 people with blood cancers like T-cell acute lymphoblastic leukemia that had come back or not resp…

This study looked at whether adding heart rate variability biofeedback (a technique to help control your heart rate) to regular physical activity could improve quality of life in people who finished treatment for blood cancer. 80 adults in remission took part. The main goal was t…

This study tested a program to help stem cell transplant survivors who have sexual problems. About 230 adults who had a transplant at least three months earlier took part. The program aimed to improve sexual function, quality of life, and mood. Results were measured using patient…

This study looked at whether a mobile phone app called Roadmap 2.0 could improve the quality of life for caregivers and patients going through a stem cell transplant. 372 caregivers and patients took part. The app was designed to provide support and track health, with the goal of…

This study looked at whether certain blood test results (blood thickness, protein ratios, and red blood cell size variation) can help predict how well people with newly diagnosed multiple myeloma will do over the next year. Researchers followed 48 patients to see if these simple …

This study involved 927 patients with blood disorders who needed a central line (a special IV). Researchers wanted to see if using a lower platelet count threshold (10,000 instead of 50,000) before the procedure would still be safe. They focused on moderate to severe bleeding eve…

This study looked at whether giving antibiotics (vancomycin) to cancer patients with a mild form of C. difficile infection helps. The infection was detected by a sensitive test but not confirmed by a toxin test. The study measured changes in C. difficile levels in stool and gut h…

This study examined 148 adults with blood diseases to identify lung complications using radiological imaging. The goal was to better understand the types and patterns of lung involvement, which can be caused by the disease itself, treatments, or other health issues. The findings …

This early-stage study tested the safety and how the body handles a new drug called RLYB116 in 16 healthy adults aged 18 to 55. Participants received multiple doses, and researchers monitored side effects, drug levels, and immune reactions. The goal was to gather safety informati…