HEMATOLOGIC DISEASES

This study tested whether adding a new drug called asciminib to the standard treatment imatinib could help patients with chronic myeloid leukemia (CML) achieve a deeper level of disease control. It involved 104 adults with CML who had been on imatinib for at least a year but hadn…

This early-phase study tested a new type of cell therapy called RD13-02 in a very small group of patients with aggressive blood cancers that had returned or not responded to standard treatments. The therapy involves modifying a patient's own immune cells to target and fight cance…

This study tested a one-time treatment using the gene-editing tool CRISPR to try to help people with severe thalassemia. Doctors took a patient's own blood stem cells, edited a gene in the lab, and then gave them back. The main goal was to see if this single treatment could allow…

This study tested whether a special breathing technique, called cardiac coherence training, combined with a tailored exercise program could improve the quality of life for adults who had been treated for blood cancers like leukemia or lymphoma. 80 participants were randomly assig…

This study looked at lung scan patterns in 148 adults with blood cancers who developed lung problems. Researchers analyzed CT scans to identify common patterns of lung damage that occur in these patients. The goal is to help doctors better recognize and understand these complicat…

This completed study aimed to see if certain blood measurements could help predict how newly diagnosed multiple myeloma patients might fare. Researchers followed 48 patients for one year after diagnosis, checking their blood thickness and protein ratios. The goal was to find conn…

This early-stage study tested the safety and how the body processes multiple doses of a new drug called RLYB116. It involved 16 healthy adults to see how well they tolerated the drug and to measure its levels and effects in the blood. The goal was to gather initial safety data be…