HEMATOLOGIC DISEASES
Clinical trials for HEMATOLOGIC DISEASES explained in plain language.
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CRISPR gene therapy aims to free patients from lifelong transfusions
Disease control Recruiting nowThis study tests a single dose of a CRISPR-based gene therapy (CTX001) in 26 adults with transfusion-dependent beta-thalassemia or severe sickle cell disease. The treatment uses the patient's own blood stem cells, which are edited to produce more fetal hemoglobin, potentially red…
Matched conditions: HEMATOLOGIC DISEASES
Phase: PHASE3 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Disease control
Last updated May 26, 2026 07:37 UTC
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Frozen testicle tissue may restore fertility in cancer survivors
Disease control Recruiting nowThis study aims to help men who became infertile after childhood cancer treatment. Researchers will transplant the patient's own testicular tissue, which was frozen before treatment, back into the scrotum. The goal is to see if the tissue can start producing sperm again. Only 5 m…
Matched conditions: HEMATOLOGIC DISEASES
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New cell therapy aims to supercharge immune recovery after stem cell transplant for young cancer patients
Disease control Recruiting nowThis early-phase study tests a cell therapy called T-allo10 given after a special stem cell transplant (αβ depleted-HSCT) in children and young adults with blood cancers. The goal is to see if it safely helps rebuild the immune system faster, without causing severe graft-versus-h…
Matched conditions: HEMATOLOGIC DISEASES
Phase: PHASE1 • Sponsor: Porteus, Matthew, MD • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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Engineered immune cells take aim at hard-to-treat leukemia
Disease control Recruiting nowThis early-stage study tests a new treatment called IL-5 CAR-T for people with a rare and aggressive blood cancer called eosinophilic leukemia that has not responded to standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and destroy ca…
Matched conditions: HEMATOLOGIC DISEASES
Phase: PHASE1 • Sponsor: Zhejiang University • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Card game helps cancer patients plan final wishes
Symptom relief Recruiting nowThis study tests whether a simple card game, called the Go Wish Game, can help people with advanced blood cancers or solid tumors talk about their end-of-life priorities with their doctors. About 75 adults will play the game and then fill out advance care planning documents. The …
Matched conditions: HEMATOLOGIC DISEASES
Phase: NA • Sponsor: Azienda USL Reggio Emilia - IRCCS • Aim: Symptom relief
Last updated May 26, 2026 07:23 UTC
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Bringing blood transfusions home: a new hospice program aims to ease End-of-Life care for blood cancer patients
Symptom relief Recruiting nowThis study tests a program that gives blood cancer patients access to blood transfusions at home while in hospice care. The goal is to see if this improves quality of life, mood, and reduces hospital visits near the end of life. About 700 adults with advanced blood cancers like l…
Matched conditions: HEMATOLOGIC DISEASES
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC