HELICOBACTER PYLORI INFECTIONS

This Phase 3 trial tests whether a new acid-reducing drug, anaprazole, works better than the standard drug esomeprazole when used with bismuth and two antibiotics to treat H. pylori infection. About 556 adults in China will take either anaprazole or esomeprazole pills twice daily…

This study tests different drug combinations to treat H. pylori, a stomach bacteria that can cause ulcers and cancer. About 88 adults with a positive stool test will receive either a standard acid blocker (proton pump inhibitor) or a newer one (vonoprazan), plus antibiotics, with…

This study compares two 14-day antibiotic treatments for Helicobacter pylori, a stomach infection that can cause ulcers and cancer. About 90 adults will receive either levofloxacin-based sequential therapy or bismuth-based quadruple therapy. The goal is to see which treatment wor…

This study tests two ways of taking amoxicillin with tegoprazan to treat H. pylori, a stomach infection that can cause ulcers. About 240 adults will take the same total daily dose of antibiotics, but one group takes it three times a day and the other twice a day. The goal is to s…

This study tests a new way to treat Helicobacter pylori (H. pylori) infections that didn't get better with the first round of antibiotics. Instead of using a scope to take a stomach sample, doctors will use a stool test to find which antibiotics will work best. About 531 adults w…

This study tests whether a 7-day course of antibiotics, chosen based on a stool test, can clear H. pylori infection as effectively as a standard 14-day course. About 544 adults with a first-time H. pylori infection will provide a stool sample for drug-resistance testing and then …

This study looks at whether a blood test for H. pylori bacteria and a painless stomach ultrasound can together predict serious complications like bleeding or a hole in the stomach from ulcers. Researchers will check 230 adults with stomach symptoms to see if these simple tests ca…

This study will measure two molecules, called miRNA-155 and miRNA-204, in stomach tissue from 100 children with ongoing belly pain. The goal is to see if these molecules are linked to gastritis (stomach inflammation) and infection with H. pylori bacteria. Researchers will use spe…

This study will check how common Helicobacter pylori infection is in 100 adults with inflammatory bowel disease (Crohn's or colitis) at the Guadeloupe hospital. Researchers will take extra stomach biopsies during routine endoscopy to study the stomach's bacteria. The goal is to s…