HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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Could a new drug help heart failure patients breathe easier and think sharper?
Disease control Not yet recruitingThis study tests whether an investigational drug (activin ligand-trap) combined with exercise training can improve exercise capacity and thinking skills in people with a type of heart failure called HFpEF. About 48 adults aged 40 and older with obesity will receive either the dru…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 26, 2026 04:19 UTC
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New device zaps lung arteries to ease heart failure
Disease control Not yet recruitingThis study tests a device that uses radiofrequency energy to calm overactive nerves in the lung arteries of people with heart failure and a specific type of high blood pressure in the lungs. About 750 adults who are stable on heart failure medications will either get the procedur…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Pulnovo Medical, Inc. • Aim: Disease control
Last updated May 26, 2026 04:19 UTC
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New heart procedure could reduce hospital stays for heart failure patients
Disease control Not yet recruitingThis study tests a procedure called pulmonary artery denervation (PADN) for people with heart failure who still have a normal pumping ability. About 310 participants will either get PADN plus standard medications or a sham procedure plus standard medications. The goal is to see i…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated May 26, 2026 04:17 UTC
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Can a common heart drug reverse hidden scarring in heart failure?
Disease control Not yet recruitingThis study looks at whether the drug sacubitril/valsartan can reduce scarring in the heart muscle of people with a type of heart failure called HFpEF. Scarring can make heart failure worse, so reducing it might improve outcomes. The study will use MRI scans to measure scarring be…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 26, 2026 04:13 UTC
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New study tests if a heart procedure can save lives in patients with both AFib and heart failure
Disease control Not yet recruitingThis study looks at 900 adults with atrial fibrillation (an irregular heartbeat) and a type of heart failure where the heart's pumping ability is mildly reduced or preserved. It compares a procedure called catheter ablation (which destroys tiny areas of heart tissue causing the i…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Tulane University • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New group exercise program aims to boost heart health in older adults
Symptom relief Not yet recruitingThis study tests a new group exercise program combined with remote activity monitoring for older adults with heart failure with preserved ejection fraction (HFpEF). The goal is to see if this approach improves exercise habits, physical function, and quality of life. Fourteen part…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated May 26, 2026 04:13 UTC
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New study explores how tirzepatide works in heart failure patients
Knowledge-focused Not yet recruitingThis study looks at how tirzepatide, a diabetes and weight-loss drug, helps people with obesity and a type of heart failure called HFpEF. Researchers will measure blood volume and body fat in 50 patients over 15 months to understand why the drug improves symptoms. The goal is to …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated May 26, 2026 04:14 UTC