HEART FAILURE, SYSTOLIC

This study looks at two ways to deliver cardiac rehabilitation—a program of exercise, education, and counseling for people with heart conditions. One method is in-person at a clinic, the other is done remotely via telehealth. The goal is to see if both approaches are equally effe…

This study compares two common heart procedures—bypass surgery (CABG) and stenting (PCI)—in 754 people with heart failure and severe blockages in multiple heart arteries. The goal is to see which approach better prevents death, stroke, heart attacks, and hospital readmissions ove…

This study looks at whether training doctors to quickly start and adjust four types of heart failure medications while patients are still in the hospital leads to better long-term treatment. About 438 adults with heart failure and reduced pumping ability will take part. The goal …

This study tests a device called Aortix, which is a small pump placed in the body to help the heart and kidneys remove excess fluid. It is for people hospitalized with worsening heart failure who still have fluid buildup despite taking strong water pills. About 320 participants w…

This study tests whether adding acetazolamide or metolazone to standard diuretic therapy helps people with acute decompensated heart failure get rid of excess fluid faster and leave the hospital sooner. About 320 adults with severe fluid overload will be randomly assigned to one …

This study is looking at whether people with psoriasis have a higher risk of heart disease. Researchers will follow 1,000 adults with psoriasis, using heart scans and blood tests to find early warning signs. The goal is to better understand the link between psoriasis and heart pr…

This study looks at how the heart handles the extreme head-down position (Trendelenburg) used during robotic pelvic surgery. Researchers will monitor 80 patients—some with normal heart function and some with heart failure—to see how their hearts perform under these conditions. Th…

This study tests whether a special pacing pattern that speeds up the heart like exercise can improve heart function in people with heart failure. 52 adults with a pacemaker or defibrillator will receive either the pacing therapy or a sham (inactive) treatment for 6 weeks. Researc…

This study looks at how your fitness level relates to the bacteria in your mouth and how well blood flows to your muscles. Researchers will collect mouth swabs, saliva, and have participants do a cycling test. The goal is to understand these connections in people with heart failu…