HEART FAILURE, SYSTOLIC

This study is testing whether a special heart pacing pattern, designed to mimic the heart rate changes during exercise, can help improve heart function in people with heart failure. Participants, who already have an implanted defibrillator, will receive either the special pacing …

This study compares two common procedures for treating severely clogged heart arteries in people whose hearts pump weakly. Researchers will follow 754 patients for about 5 years to see whether open-heart bypass surgery or less-invasive artery stenting leads to fewer deaths, strok…

This study aims to find out if a telehealth (remote) cardiac rehabilitation program works as well as the traditional in-person version. It will enroll over 500 adults with various heart conditions who are eligible for rehab. Researchers will compare how much participants improve …

This study is testing a small, temporary heart pump called Aortix against standard diuretic medications for people hospitalized with severe heart failure who are not responding well to drugs. The goal is to see if the device can help remove excess fluid from the body more effecti…

This study compares two different water pills (acetazolamide and metolazone) when added to standard heart failure treatment. Researchers want to see which helps patients with sudden worsening of heart failure get better faster, leave the hospital sooner, and have fewer side effec…

This study aims to see if training hospital doctors on the latest heart failure medication guidelines leads to better treatment for patients when they leave the hospital. Researchers will observe 438 patients with a specific type of heart failure to see if they receive the recomm…

This study aims to understand the connections between a person's fitness level, the bacteria in their mouth, and how well blood flows to their muscles. Researchers are recruiting 70 adults, including those with heart conditions, obesity, and healthy individuals, to see if fitness…

This study aims to understand how robotic surgery, which often requires patients to be tilted steeply head-down, affects heart function. Researchers will monitor 80 patients, some with normal hearts and some with heart failure, during their operations. The goal is to identify whi…

This study aims to understand how often people with psoriasis have hidden heart problems and what puts them at risk. Researchers will follow 1,000 adults with psoriasis, checking their blood for specific markers and performing detailed heart scans. The goal is to find early signs…