GRAFT FAILURE
Clinical trials for GRAFT FAILURE explained in plain language.
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New hope for sickle cell patients: drug combo may prevent transplant failure
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to a standard stem cell transplant can lower the chance of graft failure in children and young adults (ages 12-45) with severe sickle cell disease. About 24 participants will receive the treatment and be followed for 2 years. T…
Matched conditions: GRAFT FAILURE
Phase: PHASE1, PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 26, 2026 03:57 UTC
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Heart bypass showdown: which graft works best for women?
Disease control Recruiting nowThis study looks at 150 women having heart bypass surgery to see which second-best graft works better: a leg vein taken with a special 'no-touch' method or an arm artery. The goal is to find out which graft stays open longer and causes fewer complications. Results will help docto…
Matched conditions: GRAFT FAILURE
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated May 26, 2026 03:55 UTC
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New drug aims to stop transplant rejection in High-Risk patients
Disease control Recruiting nowThis early-phase study tests whether the drug emapalumab can prevent the body from rejecting a stem cell transplant in patients at high risk for graft failure. About 20 participants will receive the drug after transplant. The goal is to see if blocking a specific immune signal (i…
Matched conditions: GRAFT FAILURE
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated May 26, 2026 03:52 UTC
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New stem cell trial offers hope for sickle cell and thalassemia patients
Disease control Recruiting nowThis study tests a stem cell transplant from a healthy donor for people with serious blood disorders like sickle cell disease or thalassemia. The goal is to replace the faulty blood cells with healthy ones, reducing the need for lifelong transfusions. Participants will receive a …
Matched conditions: GRAFT FAILURE
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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New cell boost aims to rescue failed stem cell transplants
Disease control Recruiting nowThis study tests a treatment for people whose stem cell transplant did not work well or stopped working. The treatment uses a special dose of donor cells to help the body make healthy blood cells again. The study will include 21 adults and measure how well the treatment restores …
Matched conditions: GRAFT FAILURE
Phase: NA • Sponsor: NYU Langone Health • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Heart bypass patients may benefit from cheap arthritis drug
Disease control Recruiting nowThis study tests whether taking a daily low dose of colchicine (a drug usually used for gout) for one year after coronary artery bypass grafting (CABG) can reduce the chance of the new blood vessels (grafts) failing. About 100 adults who recently had bypass surgery will take colc…
Matched conditions: GRAFT FAILURE
Phase: PHASE4 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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New scan sheds light on bypass graft failure
Knowledge-focused Recruiting nowThis study looks at why vein grafts used in heart bypass surgery can narrow or fail over time. Researchers will use special full-body PET scans to see what is happening inside the grafts and how this affects the heart and body. The study involves 70 adults who recently had bypass…
Matched conditions: GRAFT FAILURE
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC