New hope for sickle cell patients: drug combo may prevent transplant failure
NCT ID NCT07252050
First seen Nov 26, 2025 · Last updated May 25, 2026 · Updated 20 times
Summary
This study tests whether adding the drug ruxolitinib to a standard stem cell transplant can lower the chance of graft failure in children and young adults (ages 12-45) with severe sickle cell disease. About 24 participants will receive the treatment and be followed for 2 years. The goal is to improve survival without needing a second transplant or facing other serious complications.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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Children's Healthcare of Atlanta
RECRUITINGAtlanta, Georgia, 30329, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's Hospital of Colorado
NOT_YET_RECRUITINGAurora, Colorado, 80045, United States
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Children's Hospital of Philadelphia
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Manning Family Children's
NOT_YET_RECRUITINGNew Orleans, Louisiana, 70118, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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