GLIOBLASTOMA (GBM)

This study is testing a new drug called BGB-58067 for people newly diagnosed with a fast-growing brain cancer called glioblastoma. The main goals are to see if the drug can get into the brain tumor and if it helps patients live longer. Participants will take the drug along with s…

This is the first-ever study in people to test the safety and best dose of a new drug called MT-125 for glioblastoma, a fast-growing brain tumor. The drug is designed to be taken alongside standard radiation therapy to try to make the radiation work better. The study will enroll …

This study is testing whether using a smaller radiation field after brain cancer surgery can control the tumor just as well as standard treatment while causing fewer side effects. It will involve 79 adults with glioblastoma who have recently had surgery. Participants will receive…

This study is testing a new gene therapy called TGX-007 for people with a fast-growing type of brain cancer called glioblastoma. The therapy uses a harmless virus to deliver two treatments directly into the tumor: one to kill cancer cells and another to activate the patient's own…

This is an early-stage study to test the safety and find the right dose of a new drug called FZ-AD005 for adults with aggressive brain tumors that have come back or stopped responding to standard treatments. The study will enroll about 40 people with high-grade gliomas, including…

This early-stage study is testing a new type of cell therapy for adults with glioblastoma that has come back after treatment. Doctors will collect a patient's own immune cells, modify them in a lab to better target the cancer, and then infuse them back. The main goals are to see …

This study is testing whether adding a new oral drug called silevertinib to standard chemotherapy (temozolomide) helps people with a specific type of aggressive brain cancer (glioblastoma) live longer without their cancer getting worse. It will involve about 162 newly diagnosed p…

This study is testing a new digital camera accessory for a surgical microscope. It aims to help neurosurgeons see suspected aggressive brain tumors more clearly during surgery. The study will observe 37 patients in Europe to see if the new tool provides better image quality and v…

This study aims to understand why glioblastoma, a severe brain cancer, is more common and aggressive in men. Researchers will analyze tumor and blood samples from 40 newly diagnosed patients to see if male hormones (androgens) influence the tumor's environment and the body's immu…

This study aims to understand the mental health challenges faced by people with glioblastoma, a serious brain cancer. Researchers will ask 176 adult patients in Germany to fill out questionnaires about depression, anxiety, suicidal thoughts, and quality of life. The goal is to id…