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New hope for aggressive brain tumors: experimental combo targets first recurrence

NCT ID NCT07431216

First seen Feb 25, 2026 · Last updated May 20, 2026 · Updated 8 times

Summary

This early-phase trial tests a new drug (STAR-001) combined with spironolactone in about 68 adults whose glioblastoma has returned after initial treatment. The goal is to see if the combination is safe and can shrink tumors. Participants receive STAR-001 by IV twice per cycle and take spironolactone pills beforehand.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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