GASTROINTESTINAL STROMAL TUMORS
Clinical trials for GASTROINTESTINAL STROMAL TUMORS explained in plain language.
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New drug shows promise in controlling advanced stomach cancer
Disease control CompletedThis study tested the drug nilotinib in 34 adults with advanced gastrointestinal stromal tumors (GIST) that could not be removed by surgery. The goal was to see if the drug could shrink or stop the growth of tumors. The results showed that some patients had their tumors shrink or…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE4 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 11:35 UTC
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New hope for Drug-Resistant GIST: paclitaxel shows promise in select patients
Disease control CompletedThis study tested the chemotherapy drug paclitaxel in 40 adults with advanced gastrointestinal stromal tumor (GIST) that had stopped responding to three standard treatments (imatinib, sunitinib, and regorafenib). The goal was to see if paclitaxel could control the disease in pati…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: Asan Medical Center • Aim: Disease control
Last updated May 26, 2026 11:27 UTC
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New combo therapy shows promise for hard-to-treat GIST
Disease control CompletedThis study tested a combination of two drugs, avelumab and axitinib, in 58 adults with advanced GIST that had stopped responding to standard treatments like imatinib and sunitinib. The goal was to see if the combination could keep the cancer from growing for at least 3 months. Th…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Phase: PHASE2 • Sponsor: Maria Sklodowska-Curie National Research Institute of Oncology • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New drug avapritinib shows promise for rare stomach cancer in chinese patients
Disease control CompletedThis study looked at how safe and effective the drug avapritinib is for Chinese patients with a rare type of stomach cancer called GIST. Researchers followed 61 patients who were already taking the drug as part of their normal care. The goal was to track side effects and see how …
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Sponsor: CStone Pharmaceuticals • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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AI reads scans and tissues to predict stomach tumor risk without surgery
Diagnosis CompletedThis study tested an artificial intelligence (AI) model that combines CT scans, digital pathology, and patient data to diagnose gastrointestinal stromal tumors (GISTs), predict their risk level, and identify genetic mutations. Researchers enrolled 300 adults with suspected stomac…
Matched conditions: GASTROINTESTINAL STROMAL TUMORS
Sponsor: Qun Zhao • Aim: Diagnosis
Last updated May 26, 2026 11:32 UTC