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New combo therapy shows promise for hard-to-treat GIST

NCT ID NCT04258956

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 23 times

Summary

This study tested a combination of two drugs, avelumab and axitinib, in 58 adults with advanced GIST that had stopped responding to standard treatments like imatinib and sunitinib. The goal was to see if the combination could keep the cancer from growing for at least 3 months. The approach aims to control the disease rather than cure it, as ongoing management is still needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Maria Sklodowska-Curie National Research Institue of Oncology

    Warsaw, 02-781, Poland

Conditions

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