GASTROINTESTINAL NEOPLASMS
Clinical trials for GASTROINTESTINAL NEOPLASMS explained in plain language.
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New combo attack on rectal cancer shows promise in reducing recurrence
Disease control CompletedThis study looked at 180 adults with rectal cancer that had spread to nearby lymph nodes. It compared a strong three-drug chemo regimen (FOLFOXIRI) plus surgery to remove affected lymph nodes against standard chemo and radiation before surgery. The goal was to see if the new appr…
Matched conditions: GASTROINTESTINAL NEOPLASMS
Phase: NA • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 26, 2026 06:49 UTC
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Gene-Edited immune cells take on stomach and colon cancers
Disease control CompletedThis study tested a new treatment for people with advanced gastrointestinal cancers that had spread and stopped responding to standard therapies. Doctors took immune cells from each patient's tumor, used CRISPR gene editing to remove a gene called CISH that slows down the immune …
Matched conditions: GASTROINTESTINAL NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: Intima Bioscience, Inc. • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Study reveals chemo delivery method may impact sleep and depression
Knowledge-focused CompletedThis study looked at 198 people with non-metastatic gastrointestinal cancer to see if taking chemotherapy as a pill (oral) or through a vein (IV) affects sleep quality and depression. Participants completed sleep and mood questionnaires before starting chemo, at 45 days, and at 9…
Matched conditions: GASTROINTESTINAL NEOPLASMS
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 06:50 UTC
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Blood tests during cancer treatment may predict side effects
Knowledge-focused CompletedThis study looked at how inflammation changes in the blood of people receiving immunotherapy for cancer. Researchers measured inflammatory markers to understand and possibly predict side effects. 98 adults with cancers like melanoma or lung cancer took part. The goal was to gathe…
Matched conditions: GASTROINTESTINAL NEOPLASMS
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC