GASTROESOPHAGEAL REFLUX
Clinical trials for GASTROESOPHAGEAL REFLUX explained in plain language.
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New supplement could help GERD patients get more Heartburn-Free days
Symptom relief OngoingThis study tests whether a supplement called PIMO (MHS-1031) can help people with GERD who still have heartburn despite taking standard acid-reducing medication (PPIs). About 247 adults will receive either PIMO or a placebo for 8 weeks, and researchers will track how many days th…
Matched conditions: GASTROESOPHAGEAL REFLUX
Phase: PHASE2 • Sponsor: Microbiome Health Sciences • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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Diet over pills? new study tests food as reflux remedy
Symptom relief OngoingThis study looks at whether the Gracie Diet can improve symptoms of gastroesophageal reflux disease (GERD) in adults who want to stop taking standard acid-reducing medications. Thirty participants will stop their usual pills and follow the diet for 8 weeks. Researchers will track…
Matched conditions: GASTROESOPHAGEAL REFLUX
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 04, 2026 16:30 UTC
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Throat reflux study pulled before starting
Knowledge-focused TerminatedThis study aimed to find better ways to diagnose and treat pharyngeal reflux, where stomach contents reach the throat. Researchers planned to measure throat muscle function and test if pressing on the throat could stop reflux. The study was withdrawn before enrolling any particip…
Matched conditions: GASTROESOPHAGEAL REFLUX
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated May 26, 2026 05:44 UTC
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500 patients donate samples to unlock secrets of weight loss and regain
Knowledge-focused OngoingThis study collects blood, urine, and tissue samples from 500 adults with obesity to help researchers learn why people gain or lose weight, and why some regain weight after treatment. Participants must be over 18 and have a BMI of 30 or higher. The samples will be stored for up t…
Matched conditions: GASTROESOPHAGEAL REFLUX
Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Knowledge-focused
Last updated May 26, 2026 05:42 UTC
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DNA clues could warn of esophageal cancer
Knowledge-focused OngoingThis study looks for early DNA changes in blood and tissue that might warn of esophageal cancer in people with Barrett's esophagus or chronic reflux. Researchers will follow 600 participants who are already having an upper endoscopy. The goal is to find markers that predict cance…
Matched conditions: GASTROESOPHAGEAL REFLUX
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC
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500 patients monitored for 10 years to check LINX reflux device safety
Knowledge-focused OngoingThis study follows 500 adults who receive the LINX device for gastroesophageal reflux disease (GERD) to track its long-term safety over 10 years. Researchers will monitor for device-related problems like swallowing difficulties, device movement, or erosion. Participants also comp…
Matched conditions: GASTROESOPHAGEAL REFLUX
Sponsor: Ethicon Endo-Surgery • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC