Gastroesophageal reflux

This study tested whether adjusting the dose of a common acid reflux medicine (lansoprazole) based on a child's genes could improve asthma control. 41 children aged 6-17 with uncontrolled asthma and mild reflux participated. Researchers measured changes in asthma symptoms and ref…

Researchers compare two drugs that reduce stomach acid, rabeprazole and omeprazole, in obese adults with gastroesophageal reflux. Participants receive a single dose of each drug, plus a placebo, and researchers measure stomach acid for 24 hours after each dose. The goal is to see…

This Phase 2 trial tests whether a prebiotic syrup called MHS-1031 (PIMO) can increase heartburn-free days when added to standard proton pump inhibitor (PPI) therapy for people with GERD. About 247 adults who still have heartburn despite taking PPIs will receive either the syrup …

This study looked at whether a swaddle blanket with a gentle abdominal band can reduce acid reflux, breathing pauses, heart rate drops, and low oxygen levels in premature infants. About 50 babies in the NICU were observed to see if the blanket helped. The goal was to find a simpl…

This study looked at 100 patients who had sleeve gastrectomy for severe obesity. Researchers checked how many developed Barrett's esophagus, a condition that can lead to esophageal cancer, five or more years after surgery. They also examined whether routine endoscopy (a camera te…

This study looked at 13 people undergoing a standard esophagus pressure test to see which breathing positions or maneuvers create the highest pressure at the junction between the esophagus and stomach. The goal is to learn how to better contract the diaphragm, which may help with…