FECAL INCONTINENCE

This study tested a new version of laparoscopic surgery to treat multiple pelvic organ prolapses in 25 women who had trouble with bowel movements. The surgery aimed to fix all prolapses at once. Patients were checked before and after surgery using exams, X-rays, and questionnaire…

This study tested a device that uses mild electrical pulses to help people with bladder or bowel control problems. 272 adults who had trouble holding urine or stool took part. The goal was to see if the device could reduce symptoms like leaks and urgency. Results showed many peop…

This study tested doing two surgeries at the same time to help children who cannot control their bowel or bladder due to nerve problems. 30 children who had not gotten better with other treatments took part. The goal was to see if the combined surgery was safe and improved their …

This study tested whether injecting botulinum toxin (like Botox) into the rectum can reduce episodes of accidental bowel leakage and urgent bathroom needs in people with fecal incontinence. Researchers enrolled 200 adults whose condition did not improve with standard treatments. …

This study tested a low-volume irrigation device (Qufora IrriSedo MiniGo) in 92 adults with fecal incontinence, chronic constipation, or both. The goal was to see if it improved bowel function and daily life. Participants used the device at home and reported their symptoms.

This study tested two treatments—biofeedback (pelvic floor exercises with guidance) and injectable bulking agents (Solesta)—for people with severe fecal incontinence (leakage of stool). 275 adults who did not improve enough with basic management were randomly assigned to one trea…

This study tested a new, more detailed method (high-resolution manometry) to measure anal muscle function in 60 people—some with fecal incontinence and some healthy. The goal was to see if this technique gives better information than older methods. Participants had their squeeze …

This early-phase study tested how two drugs, neostigmine and glycopyrrolate, move into the bloodstream when given through a skin patch (iontophoresis) compared to an IV. Six healthy adults took part to help researchers understand the drugs' behavior. The goal was to gather data f…

This study looked at 236 people, including those with chronic constipation or fecal incontinence and healthy volunteers, to better understand how the rectum and anus work. Researchers tested a new device called Fecobionics that combines several tests into one, aiming to make diag…

This study tested a new device called Fecobionics in 35 healthy adults to learn more about how the body poops normally. The device acts like artificial stool and measures pressure, angle, and timing during defecation. The goal is to gather baseline data that can help doctors bett…

This early-stage study tested whether a small, wireless patch could safely deliver two bowel medications (neostigmine and glycopyrrolate) through the skin using a tiny, unnoticeable electric current. Only 2 able-bodied volunteers took part to check safety and how the drugs enter …

This study tested two French-language questionnaires about sexuality in 298 women who had surgery for pelvic organ prolapse, urinary incontinence, or fecal incontinence. The goal was to see if these new tools accurately measure sexual function compared to an existing questionnair…