EWING SARCOMA

This early-phase study tested a new way to do stem cell transplants in 23 children whose solid tumors or lymphomas had come back. The method uses a special filter to remove certain immune cells from the donor's stem cells, aiming to help the child's body recover faster. The main …

This study tested a combination of two chemotherapy drugs, nab-paclitaxel and gemcitabine, in 59 teenagers and young adults whose sarcoma (a type of bone or soft tissue cancer) had returned or not responded to standard treatment. The main goals were to see if the drug combo could…

This study tested a combination of two drugs, olaparib and temozolomide (with or without irinotecan), in 49 adults with Ewing sarcoma or rhabdomyosarcoma that had come back or spread after standard chemotherapy. The main goal was to find the safest dose and see if the combo could…

This study tested the drug lenvatinib in 127 children, adolescents, and young adults whose solid tumors had come back or stopped responding to treatment. The goal was to see if the drug could shrink tumors and to check for side effects. Participants received lenvatinib daily, and…

This study tested two drugs, trabectedin and irinotecan, in 37 people with a type of bone cancer called Ewing sarcoma that had come back or not responded to other treatments. The goal was to find a safe dose and see if the combination could shrink tumors. Participants also receiv…

This study looked back at the medical records of 545 patients with bone tumors that had spread (metastatic). The goal was to see how these patients were treated in real life and what their outcomes were. The study focused on three types of bone tumors: osteosarcoma, Ewing sarcoma…

This study looked back at medical records of 91 children who had surgery for bone cancer in their leg between 1986 and 2017. It compared three different ways to rebuild the bone after removing the tumor: the induced membrane technique, a vascularized fibula graft, and a fibula gr…

This study followed 100 cancer patients who had surgery to remove tumors from their leg bones or soft tissues and then had the limb rebuilt. Researchers measured how independent patients became in daily activities and how well their joints moved during the first six months after …

This study looked back at the electronic health records of 700 people diagnosed with osteosarcoma or Ewing's sarcoma between 2003 and 2012. Researchers used machine learning to find patterns in the data, focusing on how long patients survived. The goal was to learn more about the…