EPILEPSY

This study looked at the long-term safety of soticlestat, an add-on seizure medicine, in children and adults with severe epilepsy syndromes like Dravet and Lennox-Gastaut. Participants took soticlestat twice daily and visited the clinic every 2-6 months. The study was terminated …

This study tested a brain implant (deep brain stimulation) to reduce seizures in people with epilepsy that is not controlled by medication. 29 participants were followed for up to 3 years to see if the device safely lowers seizure frequency. The approach uses electrical pulses to…

This study tested a medicine called lacosamide to see if it could reduce seizures in newborns (up to 28 days old) whose seizures were not controlled by standard treatments. The trial was stopped early, so results are limited. It involved 29 babies and compared lacosamide to anoth…

This study looked at whether measuring a protein called S100B in the blood right after a first seizure can help predict if someone will have more seizures within a year. Researchers enrolled 37 adults who had their first generalized seizure less than 24 hours earlier. The study w…

This study observed 97 people with drug-resistant epilepsy in the UK who had a vagus nerve stimulation (VNS) device implanted. Researchers used medical records and patient surveys to see how the therapy affected hospital visits and seizure control over time. The goal was to under…

This study tested a new dry-electrode EEG headset that people with epilepsy can use at home. Researchers compared its recording quality to standard hospital EEGs and checked if home recordings could help diagnose epilepsy. Only 5 participants were enrolled before the study ended …

This study tested a small device placed under the scalp that records brain waves for up to 12 weeks in people with epilepsy. The goal was to see if it could detect seizures as well as standard hospital monitoring and patient diaries. The study involved 64 adults with seizures sta…