Ependymoma
Clinical trials for Ependymoma explained in plain language.
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New combo therapy shows promise for kids with tough cancers
Disease control Stopped earlyThis study tested a combination of an immunotherapy drug (nivolumab) and low-dose chemotherapy in children and teenagers whose solid tumors had not responded to standard treatments. The goal was to see if the combination was safe and could help control the cancer. The trial was s…
Matched conditions: EPENDYMOMA
Phase 1/2 • Sponsor: Centre Oscar Lambret • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Can an immune booster fight rare brain tumors?
Disease control Stopped earlyThis phase 2 trial tests whether the immunotherapy drug nivolumab can shrink tumors or slow their growth in adults with rare central nervous system (brain or spine) tumors that have returned after prior treatment. Participants receive nivolumab by IV every 2 to 4 weeks for up to …
Matched conditions: EPENDYMOMA
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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New immunotherapy attempts to fight childhood brain cancer
Disease control Stopped earlyThis early-stage study tested a new immunotherapy approach for children whose ependymoma (a type of brain tumor) had come back after standard treatment. The therapy combined a peptide vaccine designed to train the immune system to attack tumor cells with a skin cream (imiquimod) …
Matched conditions: EPENDYMOMA
Phase 1 • Sponsor: James Felker • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Scientists examine stored tumor samples to uncover DNA clues in Kids' brain cancers
Knowledge-focused Stopped earlyThis study looked at stored tumor samples from 139 children with brain and central nervous system tumors. Researchers wanted to find DNA changes and biomarkers that could help understand these cancers better. The study was terminated early, so results may be limited.
Matched conditions: EPENDYMOMA
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC