EPENDYMOMA

This study looked at whether giving chemotherapy after surgery and radiation helps children with a rare brain tumor called ependymoma live longer without the cancer coming back. It included 479 children aged 1 to 21. The results showed that adding chemo did not clearly improve ou…

This early-phase study tested a new treatment for children and young adults with brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein called EGFR fou…

This study gathered health and genetic information from 326 adults with rare brain or spine tumors. Participants completed surveys about their symptoms, treatments, and lifestyle, and provided a saliva sample for DNA analysis. The goal was to better understand what causes these t…

This registry included 354 children and young adults (ages 0-21) diagnosed with medulloblastoma, CNS-PNET, or ependymoma. Its goal was to maintain high-quality diagnostic standards through central review of scans, tissue, and spinal fluid, and to collect health data and biologica…

This study tested whether analyzing the genetic makeup of a child's tumor could help doctors choose better treatments. 186 children with cancers that had come back or were not responding to standard therapy took part. The goal was to see if this approach was practical and safe, n…

This study looked at how radiation therapy changes the brains and lives of children with central nervous system tumors. Researchers followed 76 kids for up to 5 years, using MRI scans, blood and urine tests, and surveys to measure memory, quality of life, and side effects. The go…