END STAGE LIVER DISEASE
Clinical trials for END STAGE LIVER DISEASE explained in plain language.
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Vitamin e compound tested to halt liver failure in cirrhosis patients
Disease control OngoingThis study tests whether a supplement called tocotrienol (a form of vitamin E) can slow the worsening of end-stage liver disease in people with cirrhosis. About 70 adults with stable but advanced liver disease will take either tocotrienol or a placebo twice daily for 3 years. The…
Matched conditions: END STAGE LIVER DISEASE
Phase: PHASE2 • Sponsor: Chandan Sen • Aim: Disease control
Last updated Jun 22, 2026 12:08 UTC
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Texts and tools could help transplant patients take pills on time
Disease control OngoingThis study tests whether a technology-based program, along with caregiver support, can help liver transplant recipients take their medications as prescribed. Researchers will enroll 360 adults who received a liver transplant within the past 3 months. The program uses text message…
Matched conditions: END STAGE LIVER DISEASE
Phase: NA • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 22, 2026 11:57 UTC
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New registry monitors liver transplant device in thousands of patients
Disease control ENROLLING_BY_INVITATIONThis study is a registry that collects information from up to 5,000 people who received a liver transplant after the donated liver was treated with the VitaSmart HOPE system. The device keeps the liver cool and oxygenated before transplant. The goal is to see how well the device …
Matched conditions: END STAGE LIVER DISEASE
Sponsor: Bridge to Life Ltd. • Aim: Disease control
Last updated Jun 17, 2026 12:05 UTC
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Liver transplant patients may dodge kidney failure with simple drug infusion
Prevention ENROLLING_BY_INVITATIONThis study tests whether giving a drug called angiotensin 2 during liver transplant surgery can prevent acute kidney injury, a common and serious complication. About 30 adults with end-stage liver disease will be randomly assigned to receive either the drug plus standard care or …
Matched conditions: END STAGE LIVER DISEASE
Phase: PHASE4 • Sponsor: University of California, Los Angeles • Aim: Prevention
Last updated Jun 12, 2026 12:03 UTC
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Liver transplant study tests best way to manage fluids during surgery
Knowledge-focused OngoingThis pilot study compares two approaches to giving fluids during liver transplant surgery: a restrictive strategy that removes some blood early and returns it later, versus a liberal strategy that keeps blood flow high. The goal is to see if a larger study is possible by checking…
Matched conditions: END STAGE LIVER DISEASE
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:55 UTC
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Scientists track rare liver diseases to unlock clues for better care
Knowledge-focused TerminatedThis study follows children and young adults with rare mitochondrial liver diseases to learn how these conditions progress over time. Researchers collect medical data and samples to better understand the diseases, predict outcomes, and improve future treatments. The study does no…
Matched conditions: END STAGE LIVER DISEASE
Sponsor: Arbor Research Collaborative for Health • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:03 UTC