Liver transplant study tests best way to manage fluids during surgery
NCT ID NCT05647733
First seen Feb 25, 2026 · Last updated Jun 22, 2026 · Updated 15 times
Summary
This pilot study compares two approaches to giving fluids during liver transplant surgery: a restrictive strategy that removes some blood early and returns it later, versus a liberal strategy that keeps blood flow high. The goal is to see if a larger study is possible by checking recruitment rates and how well doctors follow the plan. About 138 adults with end-stage liver disease will take part across four Canadian hospitals.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centre Hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec, H2X 0C1, Canada
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London Health Sciences Centre
London, Ontario, N6G 2V4, Canada
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McGill University Health Centre
Montreal, Quebec, H4A 3J1, Canada
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Vancouver General Hospital
Vancouver, British Columbia, V5Z 1M9, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could show which fluid management method is safer for liver transplant patients and pave the way for a larger, definitive trial.
What could go wrong
This is a small pilot study focused on feasibility, not on proving which strategy is better. Results may not apply to all patients or hospitals.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.