DRY EYE DISEASE (DED)

This study compares two approved cyclosporine eye drops for dry eye disease to see which one increases the number of mucus-producing cells in the eye more. About 60 adults with dry eye will use one of the drops daily for 2 months. Researchers will measure cell changes every 2 wee…

This study tests if injecting stem cells into the eye can help people with severe dry eye caused by graft-versus-host disease (GVHD), a complication of bone marrow transplants. About 30 adults who have not improved with standard treatments will receive either one or two doses of …

This study tests a disc made from donated amniotic membrane (part of the placenta) to treat moderate to severe dry eye disease. About 40 adults who haven't gotten relief from standard eye drops will receive either the disc or usual care. The goal is to see if the disc can heal th…

This study tests a small device that attaches to a smartphone to help diagnose dry eye disease. It takes special pictures of the eye's surface using different lights. The goal is to see if people can use it at home to get accurate results, compared to a standard eye exam. About 5…

This study tests if a structured blinking exercise can reduce dry eye symptoms in adults with glaucoma who use daily eye drops. Forty-five participants will practice a specific blink routine three times a day for two weeks. Researchers will measure symptom relief and tear film st…

This study tests an experimental eye drop called BRM421 to see if it works better than artificial tears for people with dry eye disease. About 99 adults will use either BRM421 or artificial tears for 6 weeks. The main goal is to measure changes in eye surface damage and symptoms.

This study tests a new eye drop called DFL24498 in about 417 adults with dry eye disease. The drops are meant to reduce eye dryness and damage to the eye's surface. Participants will use the drops twice a day for 12 weeks, and doctors will check if their symptoms and eye health i…

This study tests whether the eye drop acoltremon can reduce dry eye symptoms in everyday life. About 60 adults with dry eye for at least 3 months will fill out surveys over 3 months. The goal is to see if the treatment improves comfort and quality of life.

This study tests whether eyedrops made from stingless bee honey (Kelulut) are safe and can help relieve dry eye symptoms. 45 adults with dry eye will use the drops three times a day for one month, while continuing their usual treatments. Researchers will check tear stability, eye…

This study tests whether VMX eye drops can improve tear film stability and reduce symptoms of dry eye disease. About 76 adults with mild to moderate dry eye will receive either VMX drops or standard treatment. The goal is to see if the drops provide better relief and improve qual…

This study tests whether doing Baduanjin (a gentle exercise) or laughter exercises, along with using artificial tears, can improve dry eye symptoms better than using artificial tears alone. About 540 adults with dry eye will take part. They will practice their assigned activity f…

This study compares two eye drop treatments—rebamipide and diquafosol—for managing dry eye disease in people having cataract surgery. About 60 adults with mild to moderate dry eye will use one of the drops for one month before and three months after surgery. The goal is to see if…

This study looks at whether having dry eye disease makes it harder for doctors to pick the right lens power before cataract surgery. Researchers will compare 100 cataract patients—some with dry eye, some without—to see if dry eye leads to less accurate vision after surgery. The g…