DIABETIC MACULAR EDEMA

This study tests a new medicine called BI 3812465 for people with diabetic macular edema, a condition that causes swelling in the center of the eye and can lead to vision loss. The trial has two parts: first, a small group gets low to high doses to check safety; then, a larger gr…

This study tests an experimental daily pill (CU06-1004) for people with diabetic macular edema, a condition that causes vision loss from fluid buildup in the eye. About 156 adults will take either a low dose, high dose, or a placebo for 24 weeks. The main goal is to see if the pi…

This study tests whether a new prefilled syringe for the drug SCD411 (a proposed biosimilar to Eylea) is easy and safe for eye doctors to use. About 33 doctors will use the syringe to treat patients with wet age-related macular degeneration, retinal vein occlusion, diabetic macul…

This study tests two different laser settings (5% vs 15% duty cycle) to treat diabetic macular edema, a condition where fluid builds up in the eye's center. About 50 adults with mild to moderate vision loss will receive one of the two laser treatments. The goal is to see which se…

This study tests whether taking a probiotic (Lactobacillus plantarum 299v) twice daily for four months can reduce retinal swelling and improve vision in people with diabetic macular edema. It involves 36 adults and compares results to past data from a control group. The goal is t…

This study tests whether a personalized care plan helps people with chronic macular diseases (like wet age-related macular degeneration or diabetic macular edema) attend their regular eye injections. Many patients skip appointments, risking vision loss. The study will enroll 200 …

This study tests an experimental drug called SNP318 in 60 people with diabetic macular edema (DME), a condition that causes vision loss due to swelling in the retina. The goal is to see if the drug is safe and can improve vision or reduce swelling compared to a placebo. Participa…

This early-stage study tests a drug called octreotide, given as a nose spray, for people with diabetic macular edema (swelling in the back of the eye) that hasn't improved with standard treatments. The goal is to see if the spray is safe and can reduce swelling and improve vision…

This study tests whether using a cotton-tipped applicator to hold the eyelid open during eye injections is less painful and faster than the standard metal speculum. About 120 adults with certain eye conditions will take part. The goal is to improve comfort and satisfaction withou…

This study looks at whether a special eye scan (OCT) can find early changes in the retina of people with diabetes who have no vision problems. About 112 participants will get a detailed eye exam, including scans and photos, to compare their eyes with healthy people. The goal is t…

This study will test a new wide field OCTA device in 200 adults with various eye diseases like age-related macular degeneration, diabetic retinopathy, and dry eye. The goal is to see if this device provides better images of blood vessels in the back and front of the eye compared …