DIABETIC MACULAR EDEMA

This study tested an experimental drug called AG-73305 in 25 adults with diabetic macular edema, a condition that causes vision loss due to diabetes. Participants received a single injection into the eye, and researchers monitored safety and vision changes over 6 months. The goal…

This study tested two different eye injections—a steroid implant (Ozurdex) and an anti-VEGF drug—to see which better controls swelling in the retina before cataract surgery in people with diabetic macular edema. Sixteen adults with diabetes and retinal swelling completed the stud…

This study looked at the long-term safety of faricimab, a medicine injected into the eye, for people with diabetic macular edema (swelling in the back of the eye caused by diabetes). About 1,500 patients who had already completed earlier studies received faricimab injections on a…

This study tested whether OCS 01 eye drops can improve vision in people with diabetic macular edema, a condition that causes swelling in the back of the eye and can lead to vision loss. About 400 adults with diabetes and eye swelling received either the active eye drop or a place…

This study tested an experimental drug called RZ402 in 94 people with diabetic macular edema, a condition that causes vision loss in people with diabetes. The goal was to see if the drug is safe and can reduce swelling in the retina and improve eyesight compared to a placebo. The…

This study tested a new eye medication called PRO-169 against a standard drug (ranibizumab) for people with diabetic macular edema, a condition that causes vision loss in people with diabetes. Over 500 adults received injections into the eye and were followed for one year to see …

This study tested an investigational drug called RO7200220 (vamikibart) given as an eye injection for people with diabetic macular edema, a condition where diabetes causes swelling in the center of the retina and blurs vision. The trial involved 394 participants and compared the …

This study tested a new drug (RO7200220) combined with a standard treatment (ranibizumab) for diabetic macular edema, a condition that causes vision loss in people with diabetes. 187 participants received either the combination or standard treatment alone. The main goal was to se…

This study tested a new way to deliver steroid medication (OXU-001) into the eye using a thin catheter, compared to a standard steroid implant (OZURDEX), in people with diabetic macular edema (swelling in the back of the eye due to diabetes). The goal was to see if the new method…

This study tested whether OCS-01 eye drops can improve vision and reduce swelling in people with diabetic macular edema, a condition that causes blurred vision in people with diabetes. The trial involved 552 participants and compared the eye drops to a placebo. The goal was to se…

This study tested the safety of aflibercept, an already-approved eye injection, in 100 Indian adults with diabetic macular edema (DME) — a condition where diabetes damages the retina and blurs vision. Participants received injections into the eye every 4 weeks for 5 months, then …

This study tested whether a higher dose (8 mg) of the eye injection aflibercept, given every 16 weeks, works as well as the standard dose (2 mg) given every 8 weeks for Chinese people with diabetic macular edema (DME). DME causes vision problems due to swelling in the back of the…

This study tested a drug called brolucizumab, given as eye injections, in 66 adults with diabetic macular edema (DME), a condition that causes vision loss in people with diabetes. The goal was to check safety and how well it works in a real-world setting in India. Participants re…

This study looked at how much of the eye medicine aflibercept enters the bloodstream when given as injections into both eyes. It included 51 adults with diabetic macular edema or age-related macular degeneration. The goal was to measure drug levels in the blood, not to test if th…

This study looked at whether special eye scans can help predict which patients with diabetic macular edema (a common cause of vision loss in diabetes) will respond best to certain treatments. Researchers analyzed images from standard eye exams of 32 participants to find patterns …

This study measured the thickness of the conjunctiva and Tenon's capsule (layers on the front of the eye) in 736 people with wet age-related macular degeneration or diabetic macular edema, as well as in healthy adults of similar age. Researchers used a special eye scanner (SD-OCT…