DIABETES TYPE 2
Clinical trials for DIABETES TYPE 2 explained in plain language.
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Could a gut procedure help control diabetes?
Disease control CompletedThis study tested a new device used during an endoscopy to regenerate the lining of the first part of the small intestine in people with type 2 diabetes. The goal was to see if the procedure is safe and could help improve blood sugar control. Twenty adults with diabetes not well …
Matched conditions: DIABETES TYPE 2
Phase: NA • Sponsor: Endogenex, Inc. • Aim: Disease control
Last updated May 26, 2026 03:04 UTC
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Weekly insulin shot could replace daily injections for diabetes
Disease control CompletedThis study tested a new insulin called icodec that is taken just once a week, compared to a standard daily insulin (glargine), in 429 adults with type 2 diabetes. Participants received either the weekly or daily insulin for 6 months. The goal was to see if the weekly insulin cont…
Matched conditions: DIABETES TYPE 2
Phase: PHASE3 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated May 26, 2026 02:47 UTC
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New study combines cultural education and smart glucose monitors to help latinx patients manage diabetes
Disease control CompletedThis study tested whether a culturally tailored diabetes education program, called Compañeros en Salud, combined with a continuous glucose monitor (CGM) helps Latinx adults with type 2 diabetes better control their blood sugar. 120 adults aged 18-60 with an A1C of 8% or higher to…
Matched conditions: DIABETES TYPE 2
Phase: NA • Sponsor: University of Washington • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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Can healthy habits in pregnancy curb weight and diabetes risk?
Disease control CompletedThis study tested two lifestyle programs for overweight or obese pregnant women to help them manage weight gain during pregnancy. 123 women participated, receiving either weekly group sessions on diet and activity or enhanced standard care. The goal was to see if these programs c…
Matched conditions: DIABETES TYPE 2
Phase: PHASE3 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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New diabetes program helps Filipino-Americans manage blood sugar
Disease control CompletedThis study tested a culturally tailored diabetes education program, called Project Dulce, combined with text message support for Filipino-Americans with type 2 diabetes. The goal was to improve diabetes knowledge, confidence, and self-care habits. Twenty-nine participants complet…
Matched conditions: DIABETES TYPE 2
Phase: NA • Sponsor: Scripps Whittier Diabetes Institute • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New weekly shot shows promise for type 2 diabetes control
Disease control CompletedThis study tested a once-weekly medicine called retatrutide in 537 adults with type 2 diabetes whose blood sugar was not well controlled by diet and exercise alone. Participants received either the study drug or a placebo for about 11 months. The main goal was to see if retatruti…
Matched conditions: DIABETES TYPE 2
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Walking away from diabetes foot pain: simple exercises show promise
Symptom relief CompletedThis study looked at whether foot-ankle exercises or walking exercises can help people with type 2 diabetes who have foot nerve problems. 375 adults with diabetes did either foot exercises, walking, or received standard care for 12 weeks. Researchers measured foot sensation, stre…
Matched conditions: DIABETES TYPE 2
Phase: NA • Sponsor: Taipei Medical University • Aim: Symptom relief
Last updated May 26, 2026 03:18 UTC
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Simple talk therapy boosts mental health in heart and diabetes patients
Symptom relief CompletedThis study tested whether problem-solving therapy (PST) — a short, practical talk therapy — could improve mental well-being in adults with type 2 diabetes or heart disease. 147 participants with poor mental health received PST in their regular doctor's office. The goal was to see…
Matched conditions: DIABETES TYPE 2
Phase: NA • Sponsor: University of Aarhus • Aim: Symptom relief
Last updated May 26, 2026 02:48 UTC
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Gene hunt aims to prevent deadly diabetes drug complication
Knowledge-focused CompletedThis study looked at the genes of 63 people with type 2 diabetes to see if certain DNA variations could predict who is at risk for diabetic ketoacidosis (DKA) when taking SGLT2 inhibitors. Researchers compared the DNA of people who had DKA while on the drug to those who did not. …
Matched conditions: DIABETES TYPE 2
Sponsor: Mount Sinai Hospital, Canada • Aim: Knowledge-focused
Last updated May 26, 2026 03:24 UTC
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Gum treatment may boost heart and diabetes health
Knowledge-focused CompletedThis study looked at whether deep cleaning of the gums (called intensive periodontal therapy) can improve not just oral health but also markers of heart disease and diabetes. About 200 adults with heart disease or type 2 diabetes received either the gum treatment or standard care…
Matched conditions: DIABETES TYPE 2
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 26, 2026 03:16 UTC
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Vitamin c may help red blood cells stay flexible in diabetes
Knowledge-focused CompletedThis study looked at how vitamin C levels in red blood cells relate to blood sugar in people with type 2 diabetes. Researchers measured red blood cell flexibility and vitamin C levels before and after 8 weeks of vitamin C and E supplements. The goal was to understand if vitamin C…
Matched conditions: DIABETES TYPE 2
Phase: NA • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC
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Study reveals COVID-19 vaccine response in immunocompromised patients
Knowledge-focused CompletedThis study looked at how well the Pfizer COVID-19 vaccine triggered an immune response in 196 adults with weakened immune systems (like kidney transplant patients or those with cancer) compared to healthy adults. Researchers measured antibody levels in the blood and nose to see i…
Matched conditions: DIABETES TYPE 2
Phase: PHASE4 • Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated May 26, 2026 03:12 UTC
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WhatsApp videos boost oral health smarts in diabetes patients
Knowledge-focused CompletedThis study tested whether a one-month educational program delivered through WhatsApp videos could improve oral health knowledge and habits in adults with type 2 diabetes. 98 participants were split into two groups: one received videos via WhatsApp, the other a brochure. After one…
Matched conditions: DIABETES TYPE 2
Phase: NA • Sponsor: Dow University of Health Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Diabetes nerve damage linked to brain fog?
Knowledge-focused CompletedThis study examined whether people with type 2 diabetes who have nerve damage (neuropathy) also have more trouble with memory and thinking. Researchers tested 101 volunteers, some with diabetes and some without, using memory quizzes, nerve checks, and brain scans. The goal was to…
Matched conditions: DIABETES TYPE 2
Sponsor: Steno Diabetes Center Copenhagen • Aim: Knowledge-focused
Last updated May 26, 2026 02:50 UTC