DIABETE TYPE 2

This early study tests if injecting a person's own stem cells into the upper gut is safe and feasible for treating type 2 diabetes. The stem cells are taken from belly fat and processed before being injected during a scope procedure. Only 15 people will take part, and the main go…

This study tests whether the drug Henggliejin can improve fatty liver in people with type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). About 149 adults will take the drug for 48 weeks to see if it reduces liver scarring. The goal is to manage the disease, not cure it.

This pilot study in Colombia will test whether a nursing program that tailors education and counseling to each patient's needs can help people with high blood pressure or type 2 diabetes stick to their medications and achieve better disease control. About 100 to 200 adults alread…

This study compares two different drug combinations for people with type 2 diabetes whose blood sugar is not well controlled with metformin and sitagliptin. About 200 adults will receive either empagliflozin or glimepiride added to their current treatment. The goal is to see whic…

This study tests a new, long-acting form of semaglutide (a diabetes drug) that is given once every four weeks instead of weekly. The goal is to see if it is safe and works well for controlling blood sugar and weight in 24 adults with type 2 diabetes. Participants must already be …

This study tests whether a daily probiotic called LP-LDL® can improve cholesterol, blood sugar, inflammation, and memory in 210 adults with prediabetes, type 1, or type 2 diabetes who also have high cholesterol or triglycerides. Participants take either the probiotic or a placebo…

This study tests a new way of managing care for older adults (ages 60-74) who have both high blood pressure and type 2 diabetes. About 960 people from rural community health centers will either receive the new integrated care package or continue with standard care. The goal is to…

This study looks at whether eating 3 dates each day for 8 weeks can improve blood sugar control and reduce oxidative stress in people with well-controlled type 2 diabetes. Researchers will replace a carbohydrate portion in the diet with dates to see if it helps without raising bl…

This study will test three approaches to reduce painful nerve damage in people with type 2 diabetes. Sixty adults aged 35-85 with moderate to severe neuropathy will receive either a special massage-like therapy (INF), a diet guided by a food sensitivity test (NVIf), or both toget…

This early-stage trial will test a new tablet that combines two common drugs—one for type 2 diabetes and one for high blood pressure—in healthy volunteers. The goal is to see if the single pill works the same in the body as taking the two drugs separately. Thirty-six healthy adul…

This early-stage study tests a new medicine called efsubaglutide alfa (YN-011) in 48 healthy adults in Brazil. The goal is to check the drug's safety, how the body processes it, and its effects. Participants receive a single injection of either the drug or a placebo and are monit…

This study monitors heart rate variability in 150 adults with type 2 diabetes who also have heart failure, chronic kidney disease, or both. Participants will wear a 24-hour heart monitor before and after starting a standard SGLT2 inhibitor medication. The goal is to understand ho…