CORONARY ARTERY DISEASE (CAD)

This study is creating a national registry to track how well a specific drug-coated heart stent (the Inspiron EVO) works in real patients with complex, blocked heart arteries. It will follow up to 2,000 people in Brazil for one year after they receive the stent to see if it succe…

This study is for people 65 and older who have had a stent placed to open a blocked heart artery. It compares two approaches to prevent blood clots after the procedure. One group takes two blood-thinning pills for just one week, then continues with only one. The other group takes…

This study aims to find out which heart procedure works better for people with weakened heart muscle and multiple blocked arteries. Researchers will compare traditional open-heart bypass surgery (CABG) against the less invasive stent procedure (PCI) in 358 patients. They will tra…

This registry study will track how well drug-coated balloons work for treating blocked heart arteries in real-world patients across Spain and Portugal. Researchers want to see if these balloons, which deliver medication directly to artery walls without leaving permanent metal ste…

This study compares two surgical approaches for patients with severe blockages in all three main heart arteries. Researchers want to see if a less invasive 'hybrid' procedure (combining small-incision bypass with artery stenting) leads to fewer complications and faster recovery t…

This study aims to see which of two common treatments works better for opening clogged heart arteries: a new type of dissolving stent or a medicated balloon. It will involve 150 patients with significant artery blockages who need treatment. Researchers will randomly assign patien…

This large German study is testing a new nationwide care model for people with new chest pain and suspected heart disease. It aims to get doctors to use safer, more accurate CT scans more often instead of invasive procedures. The goal is to see if this approach reduces heart atta…

This study is for people who have had a heart attack and received a stent, but are at high risk for both future clots and serious bleeding. It will test if using a special stent and only one month of strong blood thinners is as safe and effective as using standard stents with a f…

This study is testing a new injectable drug called SRSD107 for people with chronic coronary artery disease (CAD) or peripheral artery disease (PAD). The main goals are to see how the drug behaves in the body, if it's safe, and how it affects certain blood markers. About 104 parti…

This study aims to see if a drug-coated balloon is as good as or better than a drug-coated stent for treating blocked heart arteries in high-risk patients. It will enroll over 2,100 adults with coronary artery disease who have additional health risks like diabetes or kidney probl…

This study is testing a new, contactless technology that uses a short video scan of a person's face to measure heart health. Researchers want to see if this camera-based method is as accurate as standard blood pressure checks and cholesterol tests for estimating a person's risk o…

This study is testing how well a computer algorithm called ECGio can detect significant blockages in heart arteries. Researchers will compare ECGio's accuracy against standard imaging tests in 978 adults suspected of having heart disease. The goal is to see if this tool could hel…

This study is testing if a new drug called EA-230 can help people recover faster after major heart bypass surgery. It aims to see if patients who get the drug during surgery can leave the hospital and intensive care unit sooner and have fewer serious complications. The trial will…

This study is testing if applying an ice pack to the groin area can help patients feel better after a common heart procedure called PCI. Researchers want to see if the cold pack reduces pain and limits bruising where the catheter was inserted. They will enroll 60 adults who have …

This study aims to see if performing extra tests on heart function during a standard stent procedure leads to better relief of chest pain and improved quality of life. It will compare 450 patients who get the extra tests and targeted treatment to those who only get the standard s…

This study is testing whether a mindfulness-based stress reduction program can help women with coronary artery disease feel better. It aims to see if the program improves their quality of life, reduces anxiety, and helps them feel more empowered in managing their condition. The s…

This study aims to create better safety guidelines for blood-thinning medications given after heart stent surgery. It will follow 3,500 patients at high risk of bleeding complications for one year to see how well they tolerate the standard two-drug therapy and to test a new risk-…

This study aims to see if a simple 6-minute pegboard test is a reliable way to measure arm exercise capacity in people with coronary artery disease. Researchers will have 32 stable patients perform the pegboard test and a more complex exercise test to compare results. The goal is…

This study aims to understand if high levels of a specific blood fat called Lipoprotein(a) are linked to more calcium buildup in the heart's arteries, as seen on a special CT scan. Researchers will enroll 150 adults at intermediate risk for heart disease who are already scheduled…

This study aims to understand how repeated drops in oxygen levels during sleep in people with obstructive sleep apnea (OSA) might damage the tiny blood vessels in the heart, a condition called coronary microvascular dysfunction (CMD). Researchers will follow 560 adults with suspe…