CHOLANGIOCARCINOMA

This early-stage study is testing the safety of radiation therapy for patients with liver cancer who also have poor liver function or reduced healthy liver tissue. Researchers want to find the highest safe dose of radiation that can be given to control the cancer without causing …

This study tested pembrolizumab, an immunotherapy drug, in people with advanced solid tumors who had already tried standard treatments that stopped working. Researchers enrolled 1,609 participants with various cancers including anal, cervical, lung, and thyroid cancers to see how…

This large national trial is testing whether a combination of two immunotherapy drugs (nivolumab and ipilimumab) can help control over 50 different types of rare cancers that have few or no standard treatment options. It enrolled over 800 adults whose rare cancers had progressed …

This study is testing a drug called entrectinib for people with advanced solid tumors that have specific genetic changes (NTRK, ROS1, or ALK gene rearrangements). It's a 'basket trial,' meaning it groups patients by their tumor's genetic type rather than where the cancer started …

This study aimed to test if a personalized immune cell therapy could prevent or delay the return of advanced gastrointestinal cancers (like pancreatic, liver, or colon cancer) after standard treatment like surgery. It was for patients whose cancer had specific genetic mutations a…

This study is testing whether adding a drug called tucatinib to standard cancer treatments is safe and effective for people with HER2-positive cancers of the digestive system, like stomach, colon, and gallbladder cancers. It involves about 40 participants who have advanced cancer…

This study is testing whether a guided exercise program is safe, practical, and acceptable for older adults with liver cancer who are planning to have surgery. The main goal is to see if patients can and will participate in the program before their operation. Researchers will mea…

This early-phase study is testing a new imaging agent called 68Ga-FAPI-46 to see where it goes in the body of patients with various cancers. Researchers will give participants the tracer and then perform PET/CT scans to see how it collects in both normal and cancerous tissues. Th…

This study is testing whether a new type of blood test can help doctors monitor patients with bile duct cancer. The test looks for tiny signs of leftover cancer cells or early signs that the cancer is coming back after surgery or other treatments. Researchers will collect blood s…

This study aims to understand why some liver cancer patients respond to immunotherapy while others do not. Researchers are collecting blood, tissue, and health data from 132 adults with liver cancer who have received or will receive immunotherapy. By analyzing these samples over …