CHEMOTHERAPY

This study is for people with advanced non-small cell lung cancer (stage IIIB/C-IV) who cannot tolerate standard chemoradiation. It tests a sequence of platinum-based chemotherapy, followed by a special type of radiation (hypofractionated radiotherapy), and then the immunotherapy…

This study tests whether adding a new immunotherapy drug (cadonilimab) and low-dose radiation to standard chemotherapy can help people with advanced nasopharyngeal cancer live longer without the cancer coming back. About 380 adults aged 18-70 with newly diagnosed, advanced cancer…

This study tests whether a short course of radiation combined with immunotherapy and chemotherapy can shrink advanced gastroesophageal junction cancer enough to allow surgery. About 88 adults with locally advanced or unresectable disease will participate. The goal is to improve t…

This study looks at two ways to treat breast cancer that has spread to lymph nodes under the arm after chemotherapy. One method is surgery to remove those lymph nodes, and the other is radiation therapy. The goal is to see if radiation works just as well as surgery but causes les…

This study tests whether a blood test that detects tumor DNA can help doctors decide how long chemotherapy should last for people with certain types of colorectal cancer. About 340 adults with stage II or low-risk stage III colorectal cancer will be randomly assigned to standard …

This study is for people with advanced stomach cancer that has spread and who have already tried one prior treatment. It tests a combination of three drugs (ramucirumab, nal-IRI, and trifluridine/tipiracil) to see if they can shrink tumors and help people live longer. The trial h…

This study tests whether a treatment plan called total neoadjuvant therapy (TNT) can help about half of rectal cancer patients avoid surgery and keep their rectum. Participants receive chemotherapy and radiation before deciding if they need surgery. Those who respond very well ar…

This study tests whether a blood test that detects cancer DNA can help doctors decide on the best chemotherapy for people with high-risk stage II colorectal cancer. About 340 patients who still have cancer DNA in their blood one month after surgery will receive different chemothe…

This study is for people with high-risk stage III colorectal cancer. It uses a blood test (ctDNA) to see if adding a targeted drug (bevacizumab) to standard chemotherapy works better than chemo alone. About 100 participants will be randomly assigned to one of two treatment groups…

This study tests whether adding a natural supplement (β-hydroxybutyrate) to a standard treatment plan can help shrink or eliminate rectal cancer before surgery. The plan includes short-course radiation, immunotherapy, and chemotherapy. The goal is to see if more patients achieve …

This study tests a program called MAEva, which combines meditation and acceptance techniques, to see if it helps women with non-metastatic breast cancer feel better emotionally and physically. About 190 participants will either join the MAEva program or a discussion group for nin…

This study tests whether combining electroacupuncture with self-acupressure can improve quality of life for people with early-stage breast cancer who are undergoing chemotherapy. About 192 participants will be randomly assigned to receive the acupuncture treatment or standard car…

This study tests if acupuncture on the tongue can ease taste problems caused by chemotherapy in people with gynecologic cancer. About 75 participants will receive either real acupuncture, a fake version, or standard dietary advice. The goal is to see if acupuncture can reduce unp…

This study looks at whether painting mandalas during chemotherapy can help reduce anxiety, nausea, and improve comfort. It involves 120 adults receiving chemotherapy for the first time. Half will color mandalas for at least 30 minutes during treatment, while the other half will r…

This study tests a new program where nurses lead a team to help cancer patients be more physically active during their outpatient chemotherapy. 50 adult cancer patients will try the program, which includes activity plans, safety tips, and support materials. The goal is to see if …

This study tests whether applying herbal pastes to specific acupoints can relieve constipation and qi deficiency in people with colorectal cancer who have had chemotherapy. About 106 adults will receive either the acupoint treatment or standard care. The goal is to improve bowel …

This study compares two relaxing activities—art therapy and mandala drawing—to see which one better reduces anxiety in people receiving chemotherapy. Sixty adults currently on chemo will be randomly assigned to one of the two groups. Their anxiety levels will be measured before a…

This study tests whether a mobile app that tracks symptoms and sensor data can help people receiving chemotherapy feel better and stay connected with their care team. About 50 adults with solid tumors will use the app and a Fitbit for 90 days. The goal is to see if the app is eas…

This study is testing whether cancer patients undergoing chemotherapy can monitor their own blood counts at home instead of traveling to the hospital for every blood draw. About 265 adults with cancer from Denmark, Poland, and Germany will participate. The goal is to see if home …

This study is looking for biological markers that can predict whether a person with glioblastoma (a type of brain cancer) will survive at least 6 months after treatment with the drug bevacizumab. The study involves 170 adults whose cancer has returned after standard treatment. Re…

This study looks at how to better support adults aged 65 and older who are receiving chemotherapy. Researchers will measure each person's resilience and create a personalized care plan to meet their needs. The goal is to see if this approach helps reduce hospital stays and emerge…

This study tests a device that measures fluid in the body to see if it can better track swelling (edema) in cancer patients. Researchers will include 46 people with breast cancer or other cancers who have fluid buildup after treatment. Participants will have body measurements, bl…

This study looks back at medical records of 350 people with cervical cancer that has come back or spread to only a few places. The goal is to see if treatments like radiation or surgery, along with chemotherapy, help people live longer. Researchers want to find out which patients…