Breakthrough trial may let rectal cancer patients keep their rectum
NCT ID NCT06758830
First seen May 13, 2026 · Last updated May 25, 2026 · Updated 2 times
Summary
This study tests whether a treatment plan called total neoadjuvant therapy (TNT) can help about half of rectal cancer patients avoid surgery and keep their rectum. Participants receive chemotherapy and radiation before deciding if they need surgery. Those who respond very well are monitored closely instead of having an operation. The study involves 400 adults with early-stage rectal cancer and aims to compare quality of life, side effects, and survival between the watch-and-wait group and those who have surgery first.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Nacional Cancer Institute
RECRUITINGVilnius, 08660, Lithuania
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