CENTRAL NERVOUS SYSTEM LYMPHOMA
Clinical trials for CENTRAL NERVOUS SYSTEM LYMPHOMA explained in plain language.
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Could a rescue drug make brain cancer treatment safer?
Disease control OngoingThis study tests whether adding a drug called Voraxaze (glucarpidase) to the usual chemotherapy for central nervous system lymphoma can quickly lower methotrexate levels in the blood, potentially reducing side effects. About 58 adults with B-cell lymphoma in the brain or spinal c…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: EARLY_PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 10:33 UTC
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Radioactive drug shows promise for Hard-to-Treat blood cancers
Disease control OngoingThis study tests an experimental radioactive drug called iopofosine I 131 in people with certain blood cancers (like Waldenstrom macroglobulinemia, multiple myeloma, and lymphoma) that have come back or not responded to standard treatments. The drug is designed to target and kill…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE2 • Sponsor: Cellectar Biosciences, Inc. • Aim: Disease control
Last updated May 26, 2026 10:30 UTC
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New hope for hard-to-treat brain lymphoma: targeted drug shows promise in early trial
Disease control OngoingThis study tests a drug called acalabrutinib in 49 people with central nervous system lymphoma that has returned or not responded to prior therapy. The goal is to find the safest dose and see how well it controls the cancer. Participants take the drug by mouth and are monitored f…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New cocktail aims to attack brain lymphoma
Disease control OngoingThis study tests a combination of six drugs (TEDDI-R) for people whose aggressive B-cell lymphoma has spread to the brain or spinal cord. The goal is to see if this mix can control the cancer better than current treatments. About 48 adults with this hard-to-treat condition will t…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 20, 2026 11:55 UTC