Cardiac arrest

This trial tests whether placing a balloon in the aorta (REBOA) during CPR can improve blood flow to the heart and brain in people who have a cardiac arrest outside the hospital. The study includes 200 adults with non-traumatic cardiac arrest who receive CPR within 10 minutes. Re…

This pilot study tests whether giving packed red blood cells during in-hospital cardiac arrest can help deliver oxygen to the brain and other vital organs. Researchers plan to enroll 30 adults who have been in cardiac arrest for at least 10 minutes, comparing blood transfusions t…

This study tests whether giving sodium bicarbonate (a common substance) during a cardiac arrest in the hospital helps restart the heart. About 778 adults who have already received adrenaline will be randomly assigned to get bicarbonate or a placebo. The main goal is to see if it …

During cardiac arrest, rescuers check for a pulse by hand, but studies show this method is often wrong. This trial tests whether a carotid ultrasound in pulsed-wave Doppler mode can detect a pulse more accurately and quickly. Researchers will compare ultrasound findings with manu…

This study tests whether a balloon device, called REBOA, can be safely used by emergency teams outside a hospital to improve blood flow in people whose heart has stopped (cardiac arrest). The balloon is inserted into the main artery and inflated to redirect blood to the heart and…

This study tracks how paramedics use the ZOLL 731 ventilator when helping people with serious conditions like cardiac arrest, sepsis, or heart failure before they reach the hospital. Researchers will record which ventilator modes and settings are used, and how often alarms go off…

This study looks at how well air and blood mix in the lungs of 10 adults on a heart-lung bypass machine (VA ECMO). Researchers will adjust the breathing machine settings using special monitoring tools to see if they can improve oxygen levels. The goal is to gather information, no…

This study is looking at whether certain substances in the blood, called biomarkers, can help predict how well people recover after a cardiac arrest. Researchers will collect blood samples from about 1,500 adults treated in intensive care units after cardiac arrest. They will mea…

This large trial tests whether a coordinated community approach can improve survival and brain function after cardiac arrest. The plan includes faster 911 dispatch, CPR instructions over the phone, public CPR and AED training, and better first responder performance. About 20,000 …

This study looks at whether a simple, painless eye ultrasound can help doctors predict brain damage and survival in people who have had a cardiac arrest. Researchers will measure the optic nerve sheath diameter in 80 adults and compare it with other tests. The goal is to find a f…

This study was designed to measure blood pressure in adults experiencing cardiac arrest and to see how a device called an impedance threshold device (ITD) affects it. The ITD is placed on the airway to help blood flow to the heart. However, the study was withdrawn before enrollin…