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Eye ultrasound may predict brain damage after cardiac arrest

NCT ID NCT04838418

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a simple, painless eye ultrasound can help doctors predict brain damage and survival in people who have had a cardiac arrest. Researchers will measure the optic nerve sheath diameter in 80 adults and compare it with other tests. The goal is to find a fast, low-cost way to identify patients who may not recover, so treatment decisions can be made more accurately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Male and female patients after cardiac arrest with subsequent ROSC, 18 years of age and older

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age of 18 years or older * out of hospital cardiac arrest of non-traumatic cause with CPR and subsequent ROSC * Glasgow coma scale (GCS) ≤ 7 or sedation 30 minutes after ROSC achievment Exclusion Criteria: * unavailable first measurment of the optic nerve sheath diameter (ONSD) measured by transorbital ultrasonography 24±6 hours after ROSC achievement * refractory cardiac arrest * craniocerebral injury * intracranial tumor * active intracranial bleeding * haemorrhagic stroke and/or subarachnoid haemorrhage in the last 3 months * facial trauma affecting the eye area * active neuroendocrine tumor, small cell lung cancer, non-small cell lung * CPC 3-5 before cardiac arrest * sclerosis multiplex and/or optic neuritis of other etiology

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Plzen

    Pilsen, Czechia

More trials for these conditions

Other studies related to the condition(s) this trial covers.