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Can baking soda save lives during cardiac arrest?

NCT ID NCT05564130

Disease control Sponsor: Lars Wiuff Andersen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving sodium bicarbonate (a common substance) during a cardiac arrest in the hospital helps restart the heart. About 778 adults who have already received adrenaline will be randomly assigned to get bicarbonate or a placebo. The main goal is to see if it improves the chance of the heart beating again on its own.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 778 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2023

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. In-hospital cardiac arrest 2. Age ≥ 18 years 3. Received at least one dose of adrenaline during cardiopulmonary resuscitation (CPR) Exclusion Criteria: 1. Clearly documented "do-not-resuscitate" order prior to the cardiac arrest 2. Prior enrollment in the trial 3. Invasive mechanical circulatory support at the time of the cardiac arrest 4. Known or suspected pregnancy at the time of the cardiac arrest 5. Known objection by the patient to participate in the trial 6. Clinical indication for bicarbonate administration

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Conditions

The condition(s) this trial relates to.

cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac arrest

Contacts and locations

Locations

  • Aalborg University Hospital

    Aalborg, 9000, Denmark

  • Aarhus University Hospital

    Aarhus, 8000, Denmark

  • Copenhagen University Hospital - Bispebjerg

    Bispebjerg, 2400, Denmark

  • Copenhagen University Hospital - Gentofte

    Gentofte Municipality, 2900, Denmark

  • Copenhagen University Hospital - Herlev

    Herlev, 2730, Denmark

  • Copenhagen University Hospital - Rigshospitalet

    Copenhagen, 2100, Denmark

  • Gødstrup Hospital

    Gødstrup, 7400, Denmark

  • Holbæk Hospital

    Holbæk, 4300, Denmark

  • Horsens Regional Hospital

    Horsens, 8700, Denmark

  • Hospital of Southern Jutland - Aabenraa

    Aabenraa, 6200, Denmark

  • Hospital of Southwest Jutland - Esbjerg

    Esbjerg, 6700, Denmark

  • Hvidovre Hospital

    Hvidovre, 2650, Denmark

  • Kolding Hospital

    Kolding, 6000, Denmark

  • North Denmark Region Hospital - Hjørring

    Hjørring, 9800, Denmark

  • Nykøbing Falster Hospital

    Nykøbing Falster, 4800, Denmark

  • Odense University Hospital

    Odense, 5000, Denmark

  • Odense University Hospital - Svendborg

    Svendborg, 5700, Denmark

  • Randers Regional Hospital

    Randers, 8930, Denmark

  • Slagelse Hospital

    Slagelse, 4200, Denmark

  • Viborg Regional Hospital

    Viborg, 8800, Denmark

  • Zealand University Hospital - Køge

    Køge, 4600, Denmark

  • Zealand University Hospital - Roskilde

    Roskilde, 4000, Denmark

More trials for these conditions

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