BRONCHOPULMONARY DYSPLASIA
Clinical trials for BRONCHOPULMONARY DYSPLASIA explained in plain language.
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Lung drug tested in tiniest babies: sildenafil safety trial completed
Disease control CompletedThis study tested whether the drug sildenafil is safe for premature infants who are at risk of developing bronchopulmonary dysplasia, a chronic lung disease. A total of 109 babies born before 29 weeks of pregnancy took part. Researchers monitored side effects and measured how the…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: PHASE2 • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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Breast milk cream may help tiny preemies leave the hospital faster
Disease control CompletedThis study looked at whether adding a cream made from human milk to the feedings of extremely premature babies (born weighing 500-1250 grams) helps them leave the hospital sooner. About 210 babies were split into two groups: one got the extra cream, the other got standard feeding…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Less blood, better lungs: tiny preemies may benefit from Micro-Sampling
Disease control CompletedThis study looked at whether using very small blood samples (micro-methods) instead of standard adult-sized samples can improve health in extremely premature babies (born before 27 weeks). The goal was to reduce lung disease (bronchopulmonary dysplasia) and other serious complica…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: NA • Sponsor: David Ley • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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New drug could shield preterm lungs from chronic disease
Prevention CompletedThis study tested a new drug called rfhSP-D in 18 premature babies born before 30 weeks. The goal was to find the safest dose that might prevent chronic lung disease, a common problem in these infants. The drug was given within 12 hours of birth to babies already on a breathing m…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: PHASE1 • Sponsor: University College, London • Aim: Prevention
Last updated May 26, 2026 03:11 UTC
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Preeclampsia protein levels linked to lung problems in preterm infants
Knowledge-focused CompletedThis study looked at 33 preterm babies born before 30 weeks whose mothers had preeclampsia. Researchers measured certain proteins in the mother's blood, umbilical cord blood, and amniotic fluid to see if they were linked to a serious lung condition called bronchopulmonary dysplas…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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Preemie lungs under the microscope: 15-Year Follow-Up reveals all
Knowledge-focused CompletedThis study followed 355 teenagers who were born very early (before 32 weeks) in 1997 to see how their lungs developed. Researchers measured their breathing and lung function at age 14-15 and compared them to full-term babies. The goal was to understand long-term respiratory healt…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 26, 2026 03:19 UTC
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New imaging tech may help tiny lungs breathe free
Knowledge-focused CompletedThis study tested a non-invasive lung imaging method called Electrical Impedance Tomography (EIT) in 20 very preterm infants. Researchers wanted to see if EIT measurements could predict which babies would successfully stop breathing support by 32-33 weeks of age. The goal is to d…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: NA • Sponsor: Lawrence Rhein • Aim: Knowledge-focused
Last updated May 26, 2026 03:19 UTC
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Blood protein clues may reveal preemie lung and brain risks
Knowledge-focused CompletedThis study looked at 70 babies in the NICU to see if certain proteins called neurotrophins in their blood could predict future lung and brain development problems. Researchers measured these proteins and tracked the babies' breathing and developmental milestones. The goal was to …
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC
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Tiny trial aims to solve diuretic dilemma in preemie lungs
Knowledge-focused CompletedThis study tested a method to find out which premature babies with a chronic lung condition called bronchopulmonary dysplasia (BPD) actually benefit from diuretic medication. Nineteen babies born before 28 weeks took part in a special 'N-of-1' trial where they switched between th…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: PHASE4 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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New study tests best positions for chest therapy in premature infants
Knowledge-focused CompletedThis study looked at 60 preterm newborns in the NICU to see how different chest physiotherapy positions affect their breathing and vital signs. The goal was to find which method works best for babies with lung problems like respiratory distress or collapsed lungs. Researchers mea…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Phase: NA • Sponsor: Sanko University • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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Home air quality linked to breathing trouble in kids with lung condition
Knowledge-focused CompletedThis study looked at how indoor air quality affects breathing problems in 165 school-aged children (6-12 years old) who were born very early and have bronchopulmonary dysplasia (BPD), a chronic lung disease. Researchers measured air in the children's homes and tracked their breat…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 18, 2026 12:08 UTC
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New lung disease criteria could better predict preemie outcomes
Knowledge-focused CompletedThis study looked at 322 premature babies born before 32 weeks to compare different ways of diagnosing bronchopulmonary dysplasia (BPD), a common lung disease. The goal was to see if a new classification system that separates types of breathing support could better predict long-t…
Matched conditions: BRONCHOPULMONARY DYSPLASIA
Sponsor: Wang Jianhui • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC