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Lung drug tested in tiniest babies: sildenafil safety trial completed

NCT ID NCT03142568

First seen Mar 14, 2026 · Last updated May 23, 2026 · Updated 10 times

Summary

This study tested whether the drug sildenafil is safe for premature infants who are at risk of developing bronchopulmonary dysplasia, a chronic lung disease. A total of 109 babies born before 29 weeks of pregnancy took part. Researchers monitored side effects and measured how the drug moved through the body to understand its safety and potential effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital of Nevada at UMC

    Las Vegas, Nevada, 89106, United States

  • Cohen Children's Medical Center of NY

    New Hyde Park, New York, 11040, United States

  • Golisano Children's Hospital - University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • Health Sciences Centre Hospital

    Winnipeg, Manitoba, R3A 1R9, Canada

  • Monmouth Medical Center

    Long Branch, New Jersey, 07740, United States

  • Ochsner Baptist Medical Center

    New Orleans, Louisiana, 70115, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of Florida College of Medicine Jacksonville-Wolfson Children's Hospital

    Jacksonville, Florida, 32209, United States

  • University of Florida Jacksonville Shands Medical Center

    Jacksonville, Florida, 32209, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States

  • University of Kentucky

    Lexington, Kentucky, 40356, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • University of Oklahoma

    Oklahoma City, Oklahoma, 73104, United States

  • WakeMed Health and Hospitals

    Raleigh, North Carolina, 27610, United States

  • Wesley Medical Center

    Wichita, Kansas, 67214, United States

Conditions

Explore the condition pages connected to this study.