BREAST NEOPLASM

This study is testing a type of radiation called proton therapy for women with early-stage breast cancer. The goal is to see if it can control the cancer while causing fewer side effects than standard radiation. The trial will enroll 132 women aged 50 and older with a specific ty…

This study compares a freezing technique called cryoablation to standard lumpectomy surgery in people with low-risk, early-stage breast cancer. The goal is to see if freezing the tumor offers similar disease control with fewer complications and better quality of life. About 120 p…

This phase 2 trial at Fudan University is testing several targeted drug combinations given before surgery for early-stage breast cancer. The goal is to see if matching drugs to the tumor's specific features can improve the rate of complete cancer clearance. About 716 participants…

This study tests whether a new treatment called Bria-IMT, given with an immunotherapy drug, helps people with advanced metastatic breast cancer live longer compared to standard chemotherapy. About 404 adults whose cancer has not responded to other treatments will participate. The…

This study tests whether a special type of breast imaging called molecular breast imaging (MBI) can help doctors take tissue samples (biopsies) from breast abnormalities that are hard to see on standard ultrasound or mammogram. About 70 women with a known breast finding will part…

This study is testing a new blood test that uses laser technology and artificial intelligence to help doctors tell apart high-risk and low-risk breast cancer patients. About 330 people with breast cancer will give a blood sample before treatment. The test looks at tiny particles …

This study tests a new breast ultrasound method to see if it can better find breast cancer and track how well treatment is working. About 550 adults with suspicious breast lumps or known breast cancer will take part. The goal is to improve detection and monitor response to therap…

This study tests if a special exercise program, using bands to lightly restrict blood flow, can prevent nerve damage caused by chemotherapy in breast cancer patients. About 25 adults with HER2+ breast cancer awaiting chemo will either do these exercises or receive usual care. The…

This study tests whether drinking tart cherry juice can prevent nerve damage caused by the chemotherapy drug paclitaxel in people with breast or ovarian cancer. Participants will drink either a high or low dose of the juice daily during their 12-week chemotherapy. The goal is to …

This study compares a new breast biopsy site marker (HydroMARK Plus) with the standard marker to see if it is easier for surgeons to retrieve during surgery. About 150 women with breast cancer who need surgery will take part. The goal is to improve the marker removal process and …

This study looks at whether a guided exercise program can improve quality of life and lower healthcare costs for women with breast cancer who are undergoing treatment like surgery, chemo, or radiation. About 866 women will be split into two groups: one gets the exercise program, …

This study tests whether a 14-day mobile diary is a practical way to measure daily stress and thinking (cognitive) changes in breast cancer survivors. Researchers will enroll 30 racially diverse women aged 40 and older who are at least five years past diagnosis. Participants comp…