BREAST CANCER STAGE IV

This study tests a personalized approach for people with HER2-positive breast cancer that has spread. Doctors use blood tests (ctDNA) and scans to adjust treatments over time, adding local therapies and brain-protecting steps. The goal is to see if this can lead to long-lasting r…

This study tests a drug called datopotamab-deruxtecan in 20 people with triple-negative breast cancer that has spread to the brain. The goal is to see if the drug can shrink brain tumors. Participants must have newly diagnosed or growing brain metastases. The study is currently r…

This early-phase trial tests whether freezing a tumor (cryoablation) can boost the immune system's response to the drug pembrolizumab in people with advanced triple-negative breast cancer. About 30 participants will either receive the combination or pembrolizumab alone. The goal …

This early-stage trial is testing a new treatment for people with metastatic pancreatic or breast cancer that has spread. The treatment combines chemotherapy drugs with high-dose vitamin C and the patient's own stem cells to try to overcome drug resistance. The main goal is to ch…

This study tests different doses of the drug abemaciclib given together with radiation therapy for people with advanced hormone receptor-positive, HER2-negative breast cancer that has spread to the bone. The goal is to find the safest dose of abemaciclib when used alongside stand…

This study tests a new drug called FWD1802 in people with a specific type of advanced breast cancer (ER+/HER2-). The goal is to find a safe dose and see if it can shrink tumors. About 99 women with cancer that has spread or cannot be removed by surgery will take part.

This phase 3 trial tests whether a combination of three drugs (camrelizumab, apatinib, and eribulin) works better than standard chemotherapy for people with advanced triple-negative breast cancer. The study involves 246 participants and will measure how long the cancer stays unde…

This study tests a drug called T-DXd as the first treatment for people with HER2-positive breast cancer that has spread. About 300 participants will receive the drug and use digital tools to track side effects, especially lung issues. The goal is to see how long the drug keeps th…

This study is for people with advanced breast cancer that has spread. It tests a special PET scan that looks for a protein called HER2 on cancer cells. The goal is to see if this scan can better predict who will benefit from a targeted drug called T-DXd, helping doctors choose th…

This study tests whether drinking tart cherry juice can prevent nerve damage (neuropathy) caused by the chemotherapy drug paclitaxel in people with breast or ovarian cancer. About 86 participants will be randomly assigned to take either a high or low dose of the juice during thei…